| Cat. No. |
Product Name |
Information |
| PC-45839 |
GRA Ex-25
Glucagon receptor inhibitor
|
GRA Ex-25 is a potent glucagon receptor inhibitor with IC50 of 56 and 55 nM for rat and human glucagon receptors. |
| PC-42112 |
Glucagon receptor antagonist 1
|
Glucagon receptor antagonist 1 is a highly potent glucagon receptor antagonist. |
| PC-45758 |
PF-06291874
Glucagon receptor antagonist
|
PF-06291874 (PF-6291874) is a highly potent glucagon receptor antagonist with Ki of 14 nM for hGCGR. |
| PC-23574 |
Avexitide
GLP-1R antagonist
|
Avexitide (Exendin-(9-39)) is a selective glucagon-like peptide 1 receptor (GLP-1R) antagonist, competes with endogenous GLP-1 for binding to GLP-1 receptors with Ki of 4.0 nM. |
| PC-23495 |
BETP
GLP-1 agonist
|
BETP is a potent, allosteric activator/agonist of glucagon-like peptide-1 (GLP-1) receptor with EC50 of 0.66 and 0.755 μM for human and rat GLP-1 receptor, respectively, also inhibits importin α1 import and importin β1 dependent cargo import with EC50 of μM uM in phenotypic importin α1 translocation assays. |
| PC-23479 |
Liraglutide
GLP-1 agonist
|
Liraglutide (NN2211) is a long-acting GLP-1 analogue, glucagon-like peptide-1 (GLP-1) receptor agonist, induces lasting and reversible weight loss. |
| PC-22331 |
Lotiglipron
GLP-1R agonist
|
Lotiglipron (PF-07081532) is an oral small-molecule glucagon-like peptide-1 receptor (GLP-1R) agonist, shows potential for type 2 diabetes (T2D) and/or obesity. |
| PC-21204 |
Teduglutide
GLP-2 analogue
|
Teduglutide (ALX-0600, h[Gly(2)]GLP-2) is a dipeptidyl peptidase IV resistant GLP-2 analogue, prolongs the intestinotrophic properties of GLP-2 in animal models. |
| PC-72602 |
Cotadutide acetate
Dual GLP-1/glucagon receptor agonist
|
Cotadutide acetate (MEDI-0382, MEDI0382) is a potent dual GLP-1/glucagon receptor peptide agonist with EC50 values of 6.9 pM and 10.2 pM, respectively. |
| PC-20600 |
RGT1383
GLP-1R agonist
|
RGT1383 is a small molecule GLP-1R agonist, RGT1383 is a full agonist in G protein-mediated cAMP signaling with EC50 of 0.2 nM, and a partial agonist in β-arrestin-mediated signaling. |
| PC-20512 |
LSN3318839
GLP-1R PAM
|
LSN3318839 is a potent, positive allosteric modulator of glucagon-like peptide-1 receptor (GLP-1R) with EC50 of 14 nM, Emax of 104%. |
