| Cat. No. |
Product Name |
Information |
| PC-47501 |
Lixisenatide
GLP-1 agonist
|
Lixisenatide (ZP10A) is a peptide glucagon-like peptide 1 (GLP-1) receptor agonist. |
| PC-45831 |
MK-0893
Glucagon receptor antagonist
|
A potent, selective, reversible and competitive antagonist of glucagon receptor with high binding affinity (IC(=50=6.6 nM) and functional cAMP activity (IC50=15.7 nM). |
| PC-45745 |
Adomeglivant
GCGR antagonist
|
Adomeglivant (LY-2409021) is a potent, selective, orally active, small-molecule antagonist of human glucagon receptor with Ki of 6.66 nM. |
| PC-45839 |
GRA Ex-25
Glucagon receptor inhibitor
|
GRA Ex-25 is a potent glucagon receptor inhibitor with IC50 of 56 and 55 nM for rat and human glucagon receptors. |
| PC-42112 |
Glucagon receptor antagonist 1
|
Glucagon receptor antagonist 1 is a highly potent glucagon receptor antagonist. |
| PC-45758 |
PF-06291874
Glucagon receptor antagonist
|
PF-06291874 (PF-6291874) is a highly potent glucagon receptor antagonist with Ki of 14 nM for hGCGR. |
| PC-25559 |
YN1548
GLP-1R agonist
|
YN1548 is a potent, highly selective agonist of human glucagon-like peptide-1 receptor (GLP-1R) with EC50 of 4.59, 24.28, and 2.20 nM in CHO cells expressing low, mid, and high human GLP-1 receptor levels in a dose-dependent manner, respectively. |
| PC-25477 |
Exendin-P5
GLP-1R agonist
|
Exendin-P5 (ExP5) is a potent, selective, G protein-biased peptide agonist of GLP-1 receptor (GLP-1R), with diminished coupling to β-arrestins. |
| PC-24419 |
DA-302168S
GLP-1R agonist
|
DA-302168S is a potent, selective and orally bioavailable agonist of GLP-1R with EC50 of 1.32 nM in luciferase assay in HEK293 cells expressing hGLP-1R. |
| PC-24418 |
DD202-114
GLP-1R agonist
|
DD202-114 (HDM1002) is a potent and selective glucagon-like peptide-1 receptor (GLP-1R) agonist with EC50 of 0.03 nM in cAMP assay in HEK293 cells expressing hGLP-1R. |
| PC-24125 |
ECC5004
GLP-1 agonist
|
Elecoglipron (ECC5004/AZD5004) is a novel small‐molecule GLP‐1 receptor agonist, binds to the human GLP‐1R with IC50 of 2.4 nM, displays a full agonist profile with a potency of 2.1 nM. |
| PC-23689 |
Survodutide
GCGR/GLP-1R agonist
|
Survodutide (BI 456906) is a highly potent GCGR/GLP-1R dual agonist with EC50 of 0.52/0.60 nM respectively (human GCGR/GLP-1R), exhibits robust weight loss and glycaemic control activity. |
