| Cat. No. |
Product Name |
Information |
| PC-21069 |
Retatrutide
GIP/GLP-1/GCGR agonist
|
Retatrutide (LY3437943) is a potent, triple agonist peptide of glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R) with EC50 of 5.79 nM, 0.064 nM and 0.775 nM in cAMP assays. |
| PC-73177 |
Semaglutide
GLP-1 agonist
|
Semaglutide (NN 9535) is a glucagon-like peptide-1 (GLP-1) peptide agonist with binding IC50 of 0.38 nM, increases insulin secretion and sugar metabolism. |
| PC-72854 |
(S)-V-0219
GLP-1R PAM
|
(S)-(+)-V-0219 is an orally acitve, small molecule positive allosteric modulator (PAM) of GLP-1R. |
| PC-72853 |
V-0219
GLP-1R PAM
|
V-0219 is a small molecule positive allosteric modulator (PAM) of GLP-1R with Emax of 60% in the cAMP assay. |
| PC-72629 |
Tirzepatide
Dual GIP/GLP-1 agonist
|
Tirzepatide (LY3298176) is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, binds both receptor with high affinity (GIPR Ki=0.135; GLP-1R Ki=4.23 nM). |
| PC-72605 |
Cotadutide
Dual GLP-1/glucagon receptor agonist
|
Cotadutide (MEDI-0382, MEDI0382) is a potent dual GLP-1/glucagon receptor peptide agonist with EC50 values of 6.9 pM and 10.2 pM, respectively. |
| PC-72213 |
TT-OAD2 hydrochloride
GLP-1 agonist
|
TT-OAD2 hydrochloride is a potent, selective, non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor with EC50 of 5 nM. |
| PC-72212 |
TT-OAD2
GLP-1 agonist
|
TT-OAD2 is a potent, selective, non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor with EC50 of 5 nM. |
| PC-72211 |
LY3502970
GLP-1 agonist
|
LY3502970 (Orforglipron, OWL-833) is a potent, selective, orally active non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor. |
| PC-72210 |
Danuglipron
GLP-1R agonist
|
Danuglipron (PF-06882961) is a potent, selective, non-peptide and orally bioavailable agonist of glucagon-like peptide-1 receptor (GLP-1R) with cAMP production EC50 of 1.1 nM. |
| PC-35834 |
NLY01
2243292-26-2
|
Pegsebrenatide (NLY01) is a potent, brain-penetrant long-acting GLP1R agonist. |
| PC-43539 |
Exenatide acetate
GLP-1 agonist
|
Exenatide acetate (Exendin-4 acetate) is the acetate of Exenatide, which is highly potent, long-acting glucagon-like peptide-1 receptor (GLP-1) agonist with IC50 of 3.22 nM. |
