| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-35769 |
SR12343
|
2055101-86-3 |
SR12343 (SR-12343) is a novel NF-κB essential modulator (NEMO)-binding domain (NBD) mimetic for inhibiting IKK/NF-κB activation, inhibits TNF-α-mediated NF-κB activation with IC50 of 11.34 uM in luciferase assays. |
| PC-61282 |
AS602868
|
219773-55-4 |
AS602868 (SPC 839) is a potent, selective and ATP-competitive inhibitor of IKK2 with IC50 of 60 nM and Ki of 20 nM, also interfers directly with FLT3 kinase activation. |
| PC-61066 |
SU-909
|
2126749-48-0 |
SU-909 (SU909, IKKα-IN-48) is a potent, selective IKKα inhibitor with Ki of 0.08±0.07 uM, 10-20-fold selectivity over IKKβ (IC50=1.0±0.28 uM). |
| PC-43044 |
WS-3
|
1421227-52-2 |
WS3 is a small molecule that can induce proliferation of β cells with EC50 of 74 nM. |
| PC-42418 |
IMD-0354
|
978-62-1 |
IMD-0354 (IMD0354) is a potent IκB kinase β (IKKbeta) inhibitor, also is a potent inhibitor of glutamine uptake. |
| PC-49484 |
AFN700
|
778646-25-6 |
AFN700 (AFN 700) is a specific inhibitor of IκKβ kinase with IC50 of 0.51 uM in NF-kB reporter gene assays, inhibits TNF-a secretion produced by THP-1 cells (3h treatment with 100 ng/ml Pam3CSK4) with IC50 of 0.89 uM. |
| PC-38528 |
AZ13102909
|
2322365-47-7 |
AZ13102909 (AZ909) is a potent and selrctive TBK1 inhibitor with IC50 of 5 nM, 100-1000 fold greater for other related kinases. |
