| Cat. No. |
Product Name |
Information |
| PC-43044 |
WS-3
|
WS3 is a small molecule that can induce proliferation of β cells with EC50 of 74 nM. |
| PC-43043 |
WS6
PA2G4 inhibitor
|
WS6 is a small molecule that can induce proliferation of β cells with EC50 of 0.28 uM, also is a selective proliferation-associated 2G4 (PA2G4) inhibitor, interferes with PA2G4-MYCN binding. |
| PC-45916 |
Bay 65-1942
IKKβ inhibitor
|
Bay 65-1942 (BAY651942) is a potent, selective, ATP-competitive inhibitor of IKKβ kinase with Ki of 2 nM. |
| PC-42418 |
IMD-0354
IKKβ inhibitor, AQP4 inhibitor
|
IMD-0354 (AER-270) is a potent IκB kinase β (IKKbeta) inhibitor, also is a potent inhibitor of glutamine uptake. |
| PC-42243 |
TPCA-1
IKK-2 inhibitor
|
TPCA-1 (IKK-2 Inhibitor IV) is a potent, selective and orally bioavailable IKK-2 inhibitor with IC50 of 63 nM, TNF cell IC50 of 0.4 uM. |
| PC-42631 |
BMS-345541
IKK2 inhibitor
|
BMS-345541 is a potent and selective IKK-2 inhibitor with IC50 of 0.3 uM. |
| PC-45622 |
AZD3264
IKK2 inhibitor
|
AZD3264 is a selective small molecule inhibitor of IkB-kinase IKK2 for treatment of inflammatory conditions such as asthma, chronic pulmonary obstructive disorder (COPD) and rheumatoid arthritis. |
| PC-21476 |
Shikonin
NEMO/IKKβ inhibitor
|
Shikonin is a specific inhibitor of the IKKβ/NEMO complex PPI with IC50 of 170 nM, blocks the complex formation in vitro, in cell culture and in animal models. |
| PC-21368 |
MHPAP
IKK inhibitor
|
MHPAP is a potent cell-permeable anti-cytokine compound, inhibits inflammatory cytokines in monocyte/macrophage-like cells, directly binds to IκB kinase (IKK). |
| PC-20897 |
Wedelolactone
IKK inhibitor
|
Wedelolactone is a small molecule inhibitor of LPS-induced caspase-11 expression by directly inhibits the IKK Complex, also inhibits 5-lipoxygenase with IC50 of 2.5 uM. |
| PC-20619 |
Amlexanox
IKKε/TBK1 inhibitor
|
Amoxanox (AA-673) is a high affinity, specific inhibitor of IKKε and TBK1 with IC50 of 1-2 uM for both, without effect on IKKα or IKKβ. |
| PC-73128 |
BAY-985
TBK1/IKKε inhibitor
|
BAY-985 (BAY985) is a potent and highly selective TBK1/IKKε inhibitor with IC50 of 2 nM (low ATP assay). |
