| Cat. No. |
Product Name |
Information |
| PC-45061 |
Indoximod
IDO inhibitor
|
Indoximod (NLG-8189, 1-Methyl-D-tryptophan, D-1MT) is a potent Indoleamine 2,3-dioxygenase (IDO) inhibitor with IC50 of 7 uM. |
| PC-42226 |
8-Nitrotryptanthrin
IDO2 inhibitor
|
8-Nitrotryptanthrin (GNF-PF-3777) is a potent human indoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with Ki of 0.97 uM, also exhibits significant antitrypanosomal activities with EC50 of 0.82 uM. |
| PC-42320 |
PF-06840003
IDO1 inhibitor
|
PF-06840003 is a novel potent, selective, orally active, and CNS penetrant IDO-1 inhibitor with IC50 of 0.41 uM for hIDO-1. |
| PC-23332 |
IDO2 inhibitor 22
IDO2 inhibitor
|
IDO2 inhibitor 22 is a selective iIndoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with IC50 of 112 nM and 411 nM for IDO2 and IDO1 respectively. |
| PC-23215 |
IDO1 inhibitor VS-15
IDO1 inhibitor
|
IDO1 inhibitor VS-15 is a small molecule indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with cellular IC50 of 0.58 uM (Kyn production), not only inhibits the enzymatic but also the signaling-mediated functions of IDO1. |
| PC-22837 |
LW106
IDO1 inhibitor
|
LW106 is a selective indoleamine-2,3-dioxygenase 1 (IDO1) inhibitor with IC50 of 1.57 uM in IFN‐γ‐stimulated HeLa cells. |
| PC-22274 |
Coptisine chloride
METTL3 inhibitor, IDO inhibitor
|
Coptisine chloride is an alkaloid from Chinese goldthread, and is an efficient uncompetitive indoleamine 2,3-Dioxygenase (IDO) inhibitor, also is a potent H1N1 neuraminidase (NA-1) inhibitor with an IC50 of 104.6 μg/mL, also is a novel METTL3 inhibitor and performs therapeutic effect on periodontitis. |
