Cat. No. |
Product Name |
Information |
PC-22179 |
FCCP
Mitophagy inducer, PINK1 activator
|
FCCP is a small molecule mitochondrial uncoupler of oxidative phosphorylation (OXPHOS), induces activation of PINK1 leading to Parkin Ser65 phosphorylation, proton ionophore and mitophagy inducer. |
PC-49861 |
MTK458
PINK1 activator
|
MTK458 (MTK-458) is a potent, selective and brain penetrant PINK1 activator, MTK-458 promotes the first step in mitophagy. |
PC-62488 |
P62-mediated mitophagy inducer
Mitophagy inducer
|
P62-mediated mitophagy inducer (PMI) is a small molecule P62-mediated mitophagy inducer that activates mitophagy without recruiting Parkin or collapsing membrane potential and retains activity in cells devoid of a fully functional PINK1/Parkin pathway. |
PC-61899 |
Mtphagy Dye
|
Mtphagy Dye is a small-molecule fluorescent probe for visualizing mitophagy. |
PC-42209 |
Urolithin A
Mitophagy inducer
|
Urolithin A is a first-in-class natural compound that induces mitophagy both in vitro and in vivo following oral consumption. |
PC-23856 |
T-271
Mitophagy inducer
|
T-271 is a specific small molecule mitophagy enhancer / inducer, acts on damaged mitochondria with an EC50 of 0.94 uM, but does not directly damage normal mitochondria. |
PC-22180 |
CCCP
Mitophagy inducer, PINK1 activator
|
CCCP is a small molecule mitochondrial uncoupler of oxidative phosphorylation (OXPHOS), induces activation of PINK1 leading to Parkin Ser65 phosphorylation, proton ionophore and mitophagy inducer. |