NF-κB (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-23849	SMEPPI NF-κB p65 inhibitor	SMEPPI is a small molecule inhibitor of expression and activation of NF-κB p65, induces NF-κB p65 proteasomal degradation and has anti-diabetic and anti-inflammatory activities.
PC-22689	ZM600 HSCs activation inhibitor	ZM600 is a novel antihepatic fibrosis compound that shows significant inhibitory effect on the activation of hepatic stellate cells (HSCs), specifically inhibits the activation of NF-κB, PI-3K/AKT, and TGF-β/Smads signaling pathways.
PC-21657	CSB-0914 NF-κB inhibitor	CSB-0914 is a small molecule NF-κB inhibitor that stably binds to NF-κB-p50 subunit, exhibits significant efficacy in reducing basophil activation assay induced by FcεRI receptors with IC50 of 98.4 nM.
PC-21362	AE-848 NF-κB modualator	AE-848 is a small molecule modulator of NF-κB and PI3K/AKT/mTOR signaling pathways, shows potent in vitro and in vivo anti-myeloma activity.
PC-20991	EVP4593 nSOC inhibitor	EVP4593 (EVP-4593) is an inhibitor of PMA/PHA-induced NF-κB pathway activation with IC50 of 9 nM, inhibits storeoperated calcium (Ca2+) entry (SOC) pathway in huntington's disease (HD) neurons.
PC-45990	(R)-(-)-Ibuprofen	An enantiomer of Ibuprofen that is generally not considered a COX inhibitor and is instead thought to be involved in pathways of lipid metabolism as it is incorporated into triglycerides along with fatty acids.

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