| Cat. No. |
Product Name |
Information |
| PC-27915 |
Isoliensinine
NF-κB inhibitor, PP2A/I2PP2A inhibitor
|
Isoliensinine is a bisbenzylisoquinoline alkaloid extracted from Nelumbo nucifera Gaertn., triggers HCC cell apoptosis via inducing p65 dephosphorylation at Ser536 and inhibition of NF-κB. |
| PC-27876 |
Forsythoside B
CAS 81525-13-5
|
Forsythoside B (Forsythiaside B) is a phenylpropanoid glycoside extracted from Ballota nigra, inhibits in vitro LDL peroxidation, inhibits TNF-alpha, IL-6, IκB and modulates NF-κB, exerts potent neuroprotective effects. |
| PC-27875 |
Forsythiaside A
CAS 79916-77-1
|
Forsythiaside A is an orally active phenylethanoid glycoside isolated from the dried fruits of Forsythia suspensa within anti-inflammatory, anti-oxidant, and antioxidant activities, inhibits NF-κB activation and up-regulates the expression of Nrf2 and heme oxygenase-1 (HO-1). |
| PC-27799 |
Magnoflorine iodide
NF-κB/MAPK inhibitor
|
Magnoflorine iodide ((+)-Magnoflorine iodide) is a dietary alkaloid from Alpinia oxyphylla fruit within anxiolytics, anti-cancer, and anti-inflammatory properties, inhibits the activation of NF-κB and MAPK signaling pathways. |
| PC-27798 |
(+)-Magnoflorine chloride
NF-κB/MAPK inhibitor
|
Magnoflorine chloride ((+)-Magnoflorine) is a dietary alkaloid from Alpinia oxyphylla fruit within anxiolytics, anti-cancer, and anti-inflammatory properties, inhibits the activation of NF-κB and MAPK signaling pathways. |
| PC-27797 |
(+)-Magnoflorine
NF-κB/MAPK inhibitor
|
Magnoflorine ((+)-Magnoflorine) is a dietary alkaloid from Alpinia oxyphylla fruit within anxiolytics, anti-cancer, and anti-inflammatory properties, inhibits the activation of NF-κB and MAPK signaling pathways. |
| PC-27553 |
DYT-40
AEG-1 inhibitor, NF-κB inhibitor
|
DYT-40 is a small molecule inhibitor of Astrocyte elevated gene-1 (AEG-1) expression and NF-κB nuclear translocation, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways. |
| PC-25983 |
CARD9 inhibitor Compound 6
CARD9 inhibitor
|
CARD9 inhibitor Compound 6 is a potent, specific CARD9 inhibitor with SPR Kd of 120 nM (human CARD9), and IC50 of 0.33 uM in TR-FRET assays, blocks CARD9-dependent NF-κB activation and cytokine release. |
| PC-25329 |
RANKL inhibitor T8
RANKL inhibitor
|
RANKL inhibitor T8 is a nonpeptidic small molecular inhibitor targeting RANKL and RANK protein interaction, directly binds to RANKL with KD of 6.3 uM. |
| PC-25328 |
RANKL inhibitor 34
RANKL inhibitor
|
RANKL inhibitor 34 is a potent and selective RANKL/RANK inhibitor, displays high affinity for RANKL with SPR Kd of 614 nM, effectively inhibits RANKL-induced osteoclastogenesis and bone resorption. |
| PC-24857 |
Ro106-9920
NF-κB inhibitor
|
Ro106-9920 is a specific small molecule inhibitor of NF-kappa B-dependent cytokine expression with IC50 of <1 uM in human PBMSc, selectively inhibits IkappaB(alpha)(ee) ubiquitination with with iC50 of 2.3 uM. |
| PC-24780 |
F1929-1458
NFKB1 agonist
|
F1929-1458 is a small molecule NFKB1 (Nuclear factor κB subunit 1, NF-κB subunit 1) agonist, activates NF-κB signaling pathway, promotes anti-tumor immunity by remodeling the TME and activating DCs. |
