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Request The Product List ofNotum Notum

Cat. No. Product Name Information
PC-72827

ARUK3001185

Notum inhibitor

ARUK3001185 is a potent, selective, brain-penetrant inhibitor of Wnt-deactivating enzyme Notum carboxylesterase activity with IC50 of 6.7 nM in OPTS biochemical assay.
PC-35279

ABC99

ABC99 (NOTUM inhibitor ABC99) is a potent, selective inhibitor of the Wnt-deacylating enzyme serine hydrolase NOTUM with IC50 of 13 nM, shows excellent selectivity across the serine hydrolase family.
PC-49794

LP-914822

NOTUM inhibitor

LP-914822 (LP914822) is a potent, selective and orally-active NOTUM with IC50 of 2 nM for human, mouse and rat Notum.
PC-49793

LP-935001

NOTUM inhibitor

LP-935001 (LP935001) is a potent, selective and orally-active NOTUM with enzyme IC50 of 0.4 nM for both of human and mouse Notum.
PC-72826

LP-922056

Notum inhibitor

LP-922056 (LP922056) is a potent Notum inhibitor with IC50 of 1.1 nM in OPTS assays.
PC-72825

Notum covalent inhibitor 2

Notum inhibitor

Notum covalent inhibitor 2 is a potent, covalent Notum inhibitor with IC50 of 12 nM in OPTS assays, more poent than Notum covalent inhibitor 1.
PC-72824

Notum covalent inhibitor 1

Notum inhibitor

Notum covalent inhibitor 1 is a potent, covalent Notum inhibitor with IC50 of 93 nM in OPTS assays.
PC-72823

Notum inhibitor 23dd

Notum inhibitor

Notum inhibitor 23dd is a potent, brain-penetrant and orally active inhibitor of Notum carboxylesterase activity with IC50 of 18 nM.
PC-72822

Notum inhibitor 4d

Notum inhibitor

Notum inhibitor 4d is a highly potent inhibitor of Notum with IC50 of <10 nM, restores Wnt/β-catenin signaling in cell-based models.

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