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Cat. No. Product Name Information
PC-49556

KC289

Piezo1 activator

KC289 is a specific small-molecule agonist of PIEZO1 channel and Yoda1 analogue with EC50 of 150 nM in in calcium assays.
PC-63441

Dooku1

Piezo1 inhibitor

Dooku1 is a Yoda1 analogue that antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation, lacks agonist activity.
PC-45542

Yoda1

Piezo1 agonist

Yoda1 is a potent, selective Piezo1 ion channel activator, affects the sensitivity and the inactivation kinetics of mechanically induced responses in cells.
PC-23357

Piezo1 agonist 12a

Piezo1 agonist

Piezo1 agonist 12a is a potent small-molecule Piezo1 agonist with EC50 of 2.21 uM, 20-fold more potent than Yoda1.
PC-22518

Jedi2

Piezo1 activator

Jedi2 is a Piezo1 channel chemical activator, activates Piezo1 through interaction with extracellular regions of the peripheral blade-like domain.
PC-22517

Jedi1

Piezo1 activator

Jedi1 is a Piezo1 channel chemical activator, activates Piezo1 through interaction with extracellular regions of the peripheral blade-like domain.
PC-22516

Isoquercitrin

Piezo1 inhibitor

Isoquercitrin (Isoquercitroside) is a natural product with antioxidant and eosinophilic inflammation suppressor activity, a Piezo1 ion channel inhibitor and decreases the expression of Piezo1.

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