| Cat. No. |
Product Name |
Information |
| PC-49556 |
KC289
Piezo1 activator
|
KC289 is a specific small-molecule agonist of PIEZO1 channel and Yoda1 analogue with EC50 of 150 nM in in calcium assays. |
| PC-63441 |
Dooku1
Piezo1 inhibitor
|
Dooku1 is a Yoda1 analogue that antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation, lacks agonist activity. |
| PC-45542 |
Yoda1
Piezo1 agonist
|
Yoda1 is a potent, selective Piezo1 ion channel activator, affects the sensitivity and the inactivation kinetics of mechanically induced responses in cells. |
| PC-23357 |
Piezo1 agonist 12a
Piezo1 agonist
|
Piezo1 agonist 12a is a potent small-molecule Piezo1 agonist with EC50 of 2.21 uM, 20-fold more potent than Yoda1. |
| PC-22518 |
Jedi2
Piezo1 activator
|
Jedi2 is a Piezo1 channel chemical activator, activates Piezo1 through interaction with extracellular regions of the peripheral blade-like domain. |
| PC-22517 |
Jedi1
Piezo1 activator
|
Jedi1 is a Piezo1 channel chemical activator, activates Piezo1 through interaction with extracellular regions of the peripheral blade-like domain. |
| PC-22516 |
Isoquercitrin
Piezo1 inhibitor
|
Isoquercitrin (Isoquercitroside) is a natural product with antioxidant and eosinophilic inflammation suppressor activity, a Piezo1 ion channel inhibitor and decreases the expression of Piezo1. |
