| Cat. No. |
Product Name |
Information |
| PC-24092 |
MFaN
Otop1 modulator
|
MFaN is a potent and specific positive allosteric modulator (PAM) of proton-gated proton channel Otop1, dose-dependently potentiates mOtop1 currents with EC50 of 10.3 uM (pH 5.5). |
| PC-24038 |
Rabeprazole
Proton pump inhibitor
|
Rabeprazole (LY307640) is a second-generation proton pump inhibitor that irreversibly inactivates gastric H+/K+-ATPase, also is an uridine nucleoside ribohydrolase (UNH) inhibitor with IC50 of 0.3 uM. |
| PC-23858 |
ClGBI
Hv1 channel inhibitor
|
ClGBI is a selective blocker/inhibitor of voltage-gated proton channel Hv1 (HVCN1) with Kd of 26 uM, induces acidification of leukemic Jurkat T cells promoting cell death by apoptosis. |
| PC-23331 |
Tenatoprazole
Proton pump inhibitor
|
Tenatoprazole (TU-199) is an orally active imidazopyridine-based proton pump inhibitor, inhibits gastric H+/K+-ATPase activity with IC50 of 6.2 uM, also inhibits glutathione peroxidase 1 (GPX1). |
| PC-62893 |
CS-526
|
CS-526 (AKU 517. |
| PC-62892 |
Revaprazan
|
Revaprazan (SB-641257. |
| PC-62891 |
Revaprazan hydrochloride
|
Revaprazan (SB-641257. |
| PC-62890 |
SCH-28080
|
SCH-28080 is a potent, orally active, reversible inhibitor of gastric H+,K+-ATPase with IC50 of 20 nM. |
| PC-62889 |
PF-03716556
|
PF-03716556 is a potent, selective, competitive and reversible gastric H+,K+-ATPase with pIC50 of 7.0 in porcine ion-tight membrane vesicle. |
| PC-61362 |
Abeprazan
|
Abeprazan is an acid pump inhibitor.. |
| PC-60077 |
Azeloprazole sodium
|
A novel potent, orally active proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM. |
| PC-45145 |
Esomeprazole agnesium trihydrate
|
A proton pump inhibitor that reduces stomach acid secretion by inhibition of the H+/K+-ATPase in the parietal cells. |
