| Cat. No. |
Product Name |
Information |
| PC-49773 |
MSC-1186
SRPK inhibitor
|
MSC-1186 (MSC2711186) is a potent, highly selective pan-SRPK inhibitor with I50 of 2.7 nM, 81 nM and 0.6 nM against SRPK1, SRPK2 and SRPK3, respectively. |
| PC-35908 |
SPHINX31
SRPK1 inhibitor
|
SPHINX31 (SPHINX 31) is a potent, selective, ATP competitive inhibitor of Serine/arginine-protein kinase 1 (SRPK1) with IC50 of 5.9 nM, displays no significant activity against other splicing modulating kinases (CLK family, DYRK1A and DYRK2, DYRK5, SRPK-2/3, PIM1, PIM2 kinases). |
| PC-63234 |
SRPKIN-1
SRPK1/2 inhibitor
|
SRPKIN-1 (JH-XI-05-01) is a potent, selective, covalent SRPK1/2 inhibitor with IC50 of 35.6/98 nM, respectively. |
| PC-60568 |
SRPIN-803
SRPK1/CK2 inhibitor
|
SRPIN-803 (SRPIN 803, SRPIN803) is a novel small molecule dual inhibitor of SRPK1 and CK2 with IC50 of 2.4 uM and 0.2 uM, respectively, does not inhibit SRPK2. |
| PC-49774 |
SRPK1 inhibitor DBS1
SRPK1 inhibitor
|
SRPK1 inhibitor DBS1 (Docking Blocker of SRPK1) is a 20-mer peptide, cell-penetrating, non-ATP-competitive inhibitor of SRPK1 with ITC Kd of 5.6 uM, inhibits kinase activity of SRPK1 in a competitive manner against the substrate SRSF1 (Ki=2.12 uM), but not ATP. |
| PC-49772 |
SRPIN340
SRPK1 inhibitor
|
SRPIN340 (SRPIN 340) is a potent, highly selective inhibitor of serine-arginine-rich protein kinase (SRPK1) with Ki value of 0.89 uM (SRPK1). |
