Cat. No. |
Product Name |
Information |
PC-49215 |
CT-189
Sigma 1 inhibitor
|
CT-189 (CT189) is a drug-like analog of IPAG and small-molecule Sigma1 receptor inhibitor, binds Sigma1 with Ki value of 38 nM in [3H](+)-pentazocine binding competition assays. |
PC-47095 |
MAM03055A
Sigma 2 Receptor ligand
|
MAM03055A is a novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity, exhibits high affinity and strong preference for sigma-2 receptor with Ki of 55.9 nM. |
PC-38233 |
ANAVEX2-73
|
ANAVEX2-73 (Blarcamesine) is a Sigma-1 receptor agonist and muscarinic receptor modulator with neuroprotective effects. |
PC-35305 |
BS148
Sigma 2 receptor agonist
|
BS148 (BS-148) is a potent, selective σ2 receptor agonist with pKi of 7.71, displays 25-fold selectivity over σ1. |
PC-63494 |
JVW-1034
Sigma 2 Receptor ligand
|
JVW-1034 is a selective small molecule modulator of σ2R/Tmem97 with Ki of 23 nM, 10-fold weaker affinity for σ1R (Ki=248 nM). |
PC-63432 |
Pridopidine
|
Pridopidine (ACR16, FR-310826, ASP-2314, Huntexil) is a selective and potent Sigma-1 receptor agonist. |
PC-63205 |
MS-377
Sigma 1 receptor agonist
|
MS-377 is a potent, selective sigma-1 receptor ligand with Kd of 15.2 nM, showed anti-phencyclidine (PCP), anti-dopaminergic and anti-serotonergic activities. |
PC-63203 |
E-5842
Sigma 1 receptor agonist
|
E-5842 (E5842) is a preferential sigma-1 receptor ligand, demonstrates potential atypical antipsychotic effects in vivo. |
PC-63071 |
BD-1047 dihydrobromide
|
BD-1047 is a potent, selecitve Sigma 1 receptor (σ1) antagonist with Ki of 0.93 nM. |
PC-63070 |
BD-1047
Sigma 1 receptor antagonist
|
BD-1047 is a potent, selecitve Sigma 1 receptor (σ1) antagonist with Ki of 0.93 nM. |
PC-62223 |
Finazine
Sigma receptor ligand
|
Finazine is a high-affinity, brain penetrant sigma-1 and sigma 2 receptor ligand with Ki of 2.6 nM and 46 nM, respectively. |
PC-61602 |
4-BBPB
Sigma 1 receptor agonist
|
4-BBPB is a highly potent agonist of sigma 1 receptor (σ1 receptor) with Ki of 0.8 nM. |