| Cat. No. |
Product Name |
Information |
| PC-61601 |
4-PPBP maleate
Sigma 1 receptor agonist
|
4-PPBP maleate is a highly potent agonist of sigma 1 receptor (σ1 receptor) with Ki of 0.8 nM. |
| PC-61105 |
MIN-101
5-HT2A/Sigma 2 inhibitor
|
MIN-101 (Roluperidone, CYR-101, MT-210) is a higly potent 5-HT2A and sigma 2 receptor antagonist, with no direct dopamine affinities, for treatment of negative symptoms in schizophrenia.. |
| PC-61104 |
UKH-1114
S2R/TMEM97 agonist
|
UKH-1114 (UKH1114) is a potent, sigma 2 receptor/Tmem97 agonist with Ki of 46 nM. |
| PC-61103 |
SAS-1121
Sigma 2 Receptor ligand
|
SAS-1121 is a novel potent, subtype-selective sigma 2 receptor/PGRMC1 ligand with Ki of 16.2 nM, 574-fold selectivity over sigma 1 receptors. |
| PC-61102 |
DKR-1051
Sigma 2 Receptor ligand
|
DKR-1051 is a novel potent, subtype-selective sigma 2 receptor/PGRMC1 ligand with Ki of 61 nM, 9-fold selectivity over sigma 1 receptors (Ki=556 nM). |
| PC-61101 |
JVW-1009
Sigma receptor ligand
|
A small molecule sigma receptor ligand with Ki of 96 and 70 nM for sigma 1 and sigma 2, respectively. |
| PC-61100 |
SAS-0132
Sigma 2 Receptor ligand
|
SAS-0132 (SAS132) is a novel potent, subtype-selective, brain penetrant sigma 2 receptor/PGRMC1 ligand with Ki of 90 nM, 9-fold selectivity over sigma 1 receptors. |
| PC-60790 |
PD144418
Sigma 1 ligand
|
PD144418 (PD 144418) is a potent, selective sigma 1 ligand with Ki of 0.08 nM, >3000-fold selectivity over sigma 2 (Ki=1377 nM). |
| PC-60750 |
CM764
Sigma 2 receptor agonist
|
CM764 is a potent, selective sigma-2 receptor agonist with Ki of 3.5 nM, 25-fold selectivity over sigma-1 receptors (Ki=86.6 nM). |
| PC-60749 |
SN79
Sigma receptor antagonist
|
SN79 is a potent, orally active sigma receptor antagonist with Ki of 27 and 7 nM for σ1 and σ2, respectively. |
| PC-60748 |
CB-64D
Sigma-2 receptor agonist
|
CB-64D is a potent, selective sigma-2 receptor agonist with Ki of 16.5 nM, 200-fold selectivity over sigma 1 (Ki=3063 nM). |
| PC-60747 |
CM572
Sigma 2 receptor agonist
|
CM572 is a potent, selective, irreversible sigma-2 receptor partial agonist with Ki of 14.6 nM, >700-fold selectivity over sigma-1 receptors. |
