| Cat. No. |
Product Name |
Information |
| PC-45420 |
BD-1063 dhydrochloride
Sigma 1 receptor antagonist
|
BD-1063 dhydrochloride (BD1063) is a potent, selective sigma-1 receptor antagonist with binding Ki of 9 nM. |
| PC-45418 |
S1RA hydrochloride
Sigma 1 receptor antagonist
|
S1RA hydrochloride (E52862) is a potent and selective sigma-1 receptor (S1R) antagonist with Ki of 17 nM. |
| PC-45417 |
S1RA
Sigma 1 receptor antagonist
|
S1RA (E-52862) is a potent and selective sigma-1 receptor (S1R) antagonist with Ki of 17 nM. |
| PC-45419 |
PRE-084 hydrochloride
Sigma 1 receptor agonist
|
PRE-084 is a highly potent, selective sigma-1 receptor agonist with Ki of 2.2 nM, IC50 of 44 nM. |
| PC-42070 |
4-IBP
Sigma receptor agonist
|
4-IBP is a highly potent sigma receptor agonist with Ki of 1.7 nM and 25.2 nM for σ1 and σ2, respectively. |
| PC-23425 |
Amylovis-201
Sigma-1 agonist
|
Amylovis-201 is dual-target ligand acting as an anti-amyloidogenic compound and a potent agonist of the σ1 chaperone protein, interferes with Amyloid-β aggregation. |
| PC-22349 |
WLB-87848
Sigma 1 receptor agonist
|
WLB-87848 is a highly potent, selective, orally bioavailable sigma-1 receptor (σ1R) agonist with Ki of 9 nM, with ni significant affinity for σ2R. |
| PC-21111 |
AZ-66
Sigma receptor antagonist
|
AZ-66 is a highly potent S1R/S2R antagonist with Ki of 0.31/1.76 nM, respectively. |
| PC-21110 |
CM-304
σ2R antagonist
|
CM-304 is a potent, selective sigma-1 receptor (S1R) antagonist with Ki of 3.41 nM, 100-fold selective over S2R. |
| PC-21109 |
CM-398
σ2R ligand
|
CM-398 (CM398) is a potent, highly selective sigma-2 receptor (σ2R) ligand with Ki of 0.43 nM, >1000-fold selective over σ1R, produces antinociception and anti-allodynia effects. |
| PC-21108 |
CT-1812
σ2R ligand
|
CT-1812 (CT1812) is a potent, orally active dual σ1R and σ2R ligand with Ki of 63 and 8.5 nM respectively, IC50 of 0.31 uM in neuronal trafficking assays. |
| PC-21107 |
WLB-89462
σ2R ligand
|
WLB-89462 (WLB89462) is a potent, highly selective sigma-2 receptor (σ2R) ligand with Ki of 13 nM, >100-fold selective over σ1R (Ki=1777 nM). |
