| Cat. No. |
Product Name |
Information |
| PC-60345 |
PB28
Sigma 2 receptor agonist, Sigma 1 inhibitor
|
PB 28 is a potent, mixed sigma2 agonist and sigma1 antagonist with Ki of 0.28 and 13.0 nM, respectively. |
| PC-60289 |
NE-100 hydrochloride
Sigma 1 receptor antagonist
|
NE-100 hydrochloride is a potent, selective, and orally active sigma-1 receptor antagonist with Ki of 1.03 nM. |
| PC-60288 |
NE-100
Sigma 1 receptor antagonist
|
NE-100 is a potent, selective, and orally active sigma-1 receptor antagonist with Ki of 1.03 nM. |
| PC-60076 |
IPAG
Sigma 1 inhibitor
|
IPAG is a prototypic selective inhibitor of sigma1 receptor that engages the unfolded protein response and induces autophagy in cancer cells. |
| PC-45420 |
BD-1063 dhydrochloride
Sigma 1 receptor antagonist
|
BD-1063 dhydrochloride (BD1063) is a potent, selective sigma-1 receptor antagonist with binding Ki of 9 nM. |
| PC-45418 |
S1RA hydrochloride
Sigma 1 receptor antagonist
|
S1RA hydrochloride (E52862) is a potent and selective sigma-1 receptor (S1R) antagonist with Ki of 17 nM. |
| PC-45417 |
S1RA
Sigma 1 receptor antagonist
|
S1RA (E-52862) is a potent and selective sigma-1 receptor (S1R) antagonist with Ki of 17 nM. |
| PC-45419 |
PRE-084 hydrochloride
Sigma 1 receptor agonist
|
PRE-084 is a highly potent, selective sigma-1 receptor agonist with Ki of 2.2 nM, IC50 of 44 nM. |
| PC-42070 |
4-IBP
Sigma receptor agonist
|
4-IBP is a highly potent sigma receptor agonist with Ki of 1.7 nM and 25.2 nM for σ1 and σ2, respectively. |
| PC-25927 |
SKF83959 hydrobromide
Sigma-1 receptor PAM
|
SKF83959 hydrobromide is a potent and selective dopamine D1-like receptor partial agonist with binding Ki of 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors respectively, also is a potent allosteric modulator of Sigma 1 receptor (S1R), shows anti-seizure activities. |
| PC-25926 |
SKF83959
Sigma-1 receptor PAM
|
SKF83959 is a potent and selective dopamine D1-like receptor partial agonist with binding Ki of 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors respectively, also is a potent allosteric modulator of Sigma 1 receptor (S1R), shows anti-seizure activities. |
| PC-24306 |
CM699
DAT/σ1R antagonist
|
CM699 isa dual-action compound with σ1R antagonist effects and affinity for the DAT with Ki of 311 and 14.1 nM at DAT and σ1Rs, respectively, inhibits DA uptake ex vivo. |
