| Cat. No. |
Product Name |
Information |
| PC-45420 |
BD-1063 dhydrochloride
Sigma 1 receptor antagonist
|
BD-1063 dhydrochloride (BD1063) is a potent, selective sigma-1 receptor antagonist with binding Ki of 9 nM. |
| PC-45418 |
S1RA hydrochloride
Sigma 1 receptor antagonist
|
S1RA hydrochloride (E52862) is a potent and selective sigma-1 receptor (S1R) antagonist with Ki of 17 nM. |
| PC-45417 |
S1RA
Sigma 1 receptor antagonist
|
S1RA (E-52862) is a potent and selective sigma-1 receptor (S1R) antagonist with Ki of 17 nM. |
| PC-45419 |
PRE-084 hydrochloride
Sigma 1 receptor agonist
|
PRE-084 is a highly potent, selective sigma-1 receptor agonist with Ki of 2.2 nM, IC50 of 44 nM. |
| PC-42070 |
4-IBP
Sigma receptor agonist
|
4-IBP is a highly potent sigma receptor agonist with Ki of 1.7 nM and 25.2 nM for σ1 and σ2, respectively. |
| PC-24306 |
CM699
DAT/σ1R antagonist
|
CM699 isa dual-action compound with σ1R antagonist effects and affinity for the DAT with Ki of 311 and 14.1 nM at DAT and σ1Rs, respectively, inhibits DA uptake ex vivo. |
| PC-24212 |
Cutamesine dihydrochloride
Sigma 1 receptor agonist
|
Cutamesine dihydrochloride (SA4503, AGY94806) is a potent, selective sigma 1 receptor (σ1R) agonist, shows igh affinity for sigma 1 receptor with IC50 of 17.4 nM, 100-fold over sigma 2 receptor. |
| PC-24211 |
SA4503
Sigma 1 receptor agonist
|
SA4503 (Cutamesine, AGY 94806) is a potent, selective sigma 1 receptor (σ1R) agonist, shows igh affinity for sigma 1 receptor with IC50 of 17.4 nM, 100-fold over sigma 2 receptor. |
| PC-24026 |
Fabomotizole hydrochloride
Sigma 1 receptor agonist
|
Fabomotizole hydrochloride (Afobazole, CM346) is a compound with anxiolytic and neuroprotective activities, is an agonist of sigma1-receptor (S1R, Ki=5.9 uM). |
| PC-24025 |
Afobazole
Sigma 1 receptor agonist
|
Afobazole (Fabomotizole, CM346) is a compound with anxiolytic and neuroprotective activities, is an agonist of sigma1-receptor (S1R, Ki=5.9 uM). |
| PC-23425 |
Amylovis-201
Sigma-1 agonist
|
Amylovis-201 is dual-target ligand acting as an anti-amyloidogenic compound and a potent agonist of the σ1 chaperone protein, interferes with Amyloid-β aggregation. |
| PC-22349 |
WLB-87848
Sigma 1 receptor agonist
|
WLB-87848 is a highly potent, selective, orally bioavailable sigma-1 receptor (σ1R) agonist with Ki of 9 nM, with ni significant affinity for σ2R. |
