| Cat. No. |
Product Name |
Information |
| PC-60345 |
PB28
Sigma 2 receptor agonist, Sigma 1 inhibitor
|
PB 28 is a potent, mixed sigma2 agonist and sigma1 antagonist with Ki of 0.28 and 13.0 nM, respectively. |
| PC-60289 |
NE-100 hydrochloride
Sigma 1 receptor antagonist
|
NE-100 hydrochloride is a potent, selective, and orally active sigma-1 receptor antagonist with Ki of 1.03 nM. |
| PC-60288 |
NE-100
Sigma 1 receptor antagonist
|
NE-100 is a potent, selective, and orally active sigma-1 receptor antagonist with Ki of 1.03 nM. |
| PC-60076 |
IPAG
Sigma 1 inhibitor
|
IPAG is a prototypic selective inhibitor of sigma1 receptor that engages the unfolded protein response and induces autophagy in cancer cells. |
| PC-45420 |
BD-1063 dhydrochloride
Sigma 1 receptor antagonist
|
BD-1063 dhydrochloride (BD1063) is a potent, selective sigma-1 receptor antagonist with binding Ki of 9 nM. |
| PC-45418 |
S1RA hydrochloride
Sigma 1 receptor antagonist
|
S1RA hydrochloride (E52862) is a potent and selective sigma-1 receptor (S1R) antagonist with Ki of 17 nM. |
| PC-45417 |
S1RA
Sigma 1 receptor antagonist
|
S1RA (E-52862) is a potent and selective sigma-1 receptor (S1R) antagonist with Ki of 17 nM. |
| PC-45419 |
PRE-084 hydrochloride
Sigma 1 receptor agonist
|
PRE-084 is a highly potent, selective sigma-1 receptor agonist with Ki of 2.2 nM, IC50 of 44 nM. |
| PC-42070 |
4-IBP
Sigma receptor agonist
|
4-IBP is a highly potent sigma receptor agonist with Ki of 1.7 nM and 25.2 nM for σ1 and σ2, respectively. |
| PC-27163 |
LMH-2
Sigma-1 receptor antagonist
|
LMH-2 is a potent, selective sigma-1 receptor (σ1 R) antagonist with Ki of 6.0 nM, shows high σ1R/σ2R selectivity ratio, displays antihyperalgesic and antiallodynic effects. |
| PC-27162 |
BMY-14802 hydrochloride
Sigma-1 antagonist
|
BMY-14802 hydrochloride is a potent sigma-1 receptor (σ1R) antagonist with IC50 of 112 nM, also an agonist at serotonin 5-HT1A (IC50=320 nM) and adrenergic α-1 receptor (IC50=460 nM). |
| PC-27161 |
BMY-14802
Sigma-1 antagonist
|
BMY-14802 is a potent sigma-1 receptor (σ1R) antagonist with IC50 of 112 nM, also an agonist at serotonin 5-HT1A (IC50=320 nM) and adrenergic α-1 receptor (IC50=460 nM). |
