Cat. No. |
Product Name |
Information |
PC-21110 |
CM-304
σ2R antagonist
|
CM-304 is a potent, selective sigma-1 receptor (S1R) antagonist with Ki of 3.41 nM, 100-fold selective over S2R. |
PC-21109 |
CM-398
σ2R ligand
|
CM-398 (CM398) is a potent, highly selective sigma-2 receptor (σ2R) ligand with Ki of 0.43 nM, >1000-fold selective over σ1R, produces antinociception and anti-allodynia effects. |
PC-21108 |
CT-1812
σ2R ligand
|
CT-1812 (CT1812) is a potent, orally active dual σ1R and σ2R ligand with Ki of 63 and 8.5 nM respectively, IC50 of 0.31 uM in neuronal trafficking assays. |
PC-21107 |
WLB-89462
σ2R ligand
|
WLB-89462 (WLB89462) is a potent, highly selective sigma-2 receptor (σ2R) ligand with Ki of 13 nM, >100-fold selective over σ1R (Ki=1777 nM). |
PC-21055 |
RC-752
Sigma 1 inhibitor
|
RC-752 is a potent, seletive sigma-1 receptor (S1R) antagonist with Ki of 6.2 nM, 50-fold selective over S2R, shows antinociceptive activity. |
PC-20968 |
GM310
Sigma-1 agonist
|
GM310 is a small molecule inhibitor of glycolysis, proteotoxicity, inflammation, and impairments in animal models of Alzheime's, Huntington's, and stroke by activation of the Sigma-1 receptor. |