| Cat. No. |
Product Name |
Information |
| PC-72081 |
FGIN-1-27
TSPO agonist
|
FGIN-1-27 (FGIN 1-27) is an anxiolytic compound that acts as a selective agonist at the peripheral benzodiazepine receptor (TSPO) with Ki of 5 nM. |
| PC-62205 |
Diazepinomicin
Ras-RAF-MAPK inhibitor
|
Diazepinomicin (TLN 4601, ECO-4601) is a brain penetrant inhibitor of Ras-RAF-MAPK pathway post Ras prenylation and prior to MEK activation, binds the central and/or peripheral benzodiazepine receptors (PBR, TSPO). |
| PC-62197 |
DPA-714
TSPO ligand
|
DPA-714 is a potent, selective ligand for the translocator protein (TSPO) with Ki of 7.0 nM. |
| PC-60733 |
TSPO agonist CB34
TSPO agonist
|
TSPO agonist CB34 is a potent, selective translocator protein 18 kDa (TSPO/PBR) agonist with IC50 of 2.59 and 1.03 nM in competing with [3H]-PK11195 for binding to membrane preparations from rat cerebral cortex and ovary, respectively. |
| PC-60732 |
ONO-2952
TSPO inhibitor
|
ONO-2952 is a novel potent, selective, orally active translocator protein 18 kDa (TSPO/PBR) antagonist with Ki of 0.33-9.3 nM for both rat and human TSPO, respectively. |
| PC-60195 |
Ro5-4864
TSPO ligand
|
Ro5-4864 is a potent, selective ligand for the mitochondrial translocator protein 18kDa (TSPO/PBR). |
| PC-60185 |
PK-11195
TSPO ligand
|
PK-11195 (PK 11195) is an isoquinoline carboxamide that binds selectively to PBR (TSPO) with Ki of 3.1 nM in cerebellum, 4.1 nM in spinal cord. |
| PC-70052 |
DAA-1097
TSPO agonist
|
DAA-1097 is a potent, selective agonist of peripheral benzodiazepine receptor (PBR, TSPO) that inhibits [3H]PK 11195 binding to crude mitochondrial preparations of rat whole brain with IC50 of 0.92 nM. |
| PC-45756 |
DAA-1106
TSPO agonist
|
DAA-1106 is a potent, selective agonist of PBR/TSPO that inhibits [3H]PK 11195 binding to crude mitochondrial preparations of rat whole brain with IC50 of 0.92 nM. |
| PC-22700 |
XBD173
TSPO agonist
|
XBD173 (Emapunil, AC-5216) is a selective, orally active 18 kDa translocator protein (TSPO) ligand/agonist, shows antianxiety and antidepressant-like effects. |
