| Cat. No. |
Product Name |
Information |
| PC-73399 |
RP-6306
PKMYT1 inhibitor
|
RP-6306 (Lunresertib, RP6306) is a first-in-class, potent and selective, orally available inhibitor of PKMYT1 with IC50 of 2.4 nM, displays less potency (>35-fold) against EphA1-2, and EphB2-4, and Wee1. |
| PC-72320 |
Azenosertib
Wee1 inhibitor
|
Azenosertib (ZN-c3, Wee1 inhibitor ZN-c33) is a highly potent, selective Wee1 inhibitor with IC50 of 3.8 nM. |
| PC-72319 |
Wee1 Inhibitor II
Wee1 inhibitor
|
Wee1 Inhibitor II is a potent, selective, ATP-binding site-targeting inhibitor of Wee1 with IC50 of 59 nM, 590-fold selectivity over the related checkpoint kinase Chk1 (IC50=35 uM). |
| PC-72318 |
Debio 0123
Wee1 inhibitor
|
Debio 0123 (Debio0123) is a potent, orally available, and highly selective Wee1 kinase inhibitor with IC50 of 0.8 nM, Ki of 0.1 nM. |
| PC-35251 |
WEE1Hu inhibitor 1
WEE1Hu inhibitor
|
WEE1Hu inhibitor is a novel potent inhibitor of WEE1Hu kinase (also known as Wee1A) with IC50 of 68 nM against recombined WEE1Hu in ELISA assays. |
| PC-42770 |
Adavosertib
Wee1 inhibitor
|
Adavosertib (AZD-1775;MK-1775) is a potent and selective small-molecule inhibitor of Wee1 kinase with IC50 of 5.2 nM. |
