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Cat. No. Product Name Information
PC-73399

RP-6306

PKMYT1 inhibitor

RP-6306 (Lunresertib, RP6306) is a first-in-class, potent and selective, orally available inhibitor of PKMYT1 with IC50 of 2.4 nM, displays less potency (>35-fold) against EphA1-2, and EphB2-4, and Wee1.
PC-72320

ZN-c3

Wee1 inhibitor

Azenosertib (ZN-c3, Wee1 inhibitor ZN-c33) is a highly potent, selective Wee1 inhibitor with IC50 of 3.8 nM.
PC-72318

Debio 0123

Wee1 inhibitor

Debio 0123 (Debio0123) is a potent, orally available, and highly selective Wee1 kinase inhibitor with IC50 of 0.8 nM, Ki of 0.1 nM.
PC-42770

Adavosertib

Wee1 inhibitor

Adavosertib (AZD-1775;MK-1775) is a potent and selective small-molecule inhibitor of Wee1 kinase with IC50 of 5.2 nM.
PC-72319

Wee1 Inhibitor II

Wee1 inhibitor

Wee1 Inhibitor II is a potent, selective, ATP-binding site-targeting inhibitor of Wee1 with IC50 of 59 nM, 590-fold selectivity over the related checkpoint kinase Chk1 (IC50=35 uM).
PC-35251

WEE1Hu inhibitor

WEE1Hu inhibitor is a novel potent inhibitor of WEE1Hu kinase (also known as Wee1A) with IC50 of 68 nM against recombined WEE1Hu in ELISA assays.

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