| Cat. No. |
Product Name |
Information |
| PC-60656 |
SOMG-833
c-Met inhibitor
|
Zgwatinib (SOMG833) is a potent, selective, ATP-competitive c-MET inhibitor with IC50 of 0.93 nM. |
| PC-60463 |
SAR125844
c-Met inhibitor
|
SAR125844 is a potent, highly selective, ATP-competitive MET receptor tyrosine kinase inhibitor with IC50 of 4.2 nM. |
| PC-70080 |
Glesatinib
AXL/c-Met inhibitor
|
Glesatinib (MGCD-265) is a tyrosine kinase inhibitor that potently and selectively inhibits Met and Axl kinase. |
| PC-60074 |
Glumetinib
c-Met inhibitor
|
Glumetinib (SCC244) is a novel potent and highly selective inhibitor of c-Met kinase with IC50 of 0.42 nM. |
| PC-45668 |
Glesatinib hydrochloride
AXL/c-Met inhibitor
|
Glesatinib (MGCD265) hydrochloride is a tyrosine kinase inhibitor that potently and selectively inhibits c-Met and Axl kinase. |
| PC-45885 |
Crizotinib
c-Met inhibitor
|
Crizotinib (PF-02341066;PF-2341066) is a potent, selective, orally bioavailable, ATP-competitive inhibitor of c-Met catalytic activity with Ki of 4 nM. |
| PC-45842 |
Tivantinib
c-Met inhibitor
|
Tivantinib (ARQ-197) is a potent, selective, non-ATP-competitive inhibitor of c-Met with Ki of 355 nM. |
| PC-45841 |
JNJ-38877605
MET inhibitor
|
JNJ-38877605 is a potent, selective, ATP-competitive inhibitor of catalytic activity c-Met with IC50 of 4 nM. |
| PC-42535 |
Foretinib
c-Met inhibitor
|
Foretinib (XL880, GSK1363089, GSK089, EXEL-2880) is a potent, multikinase inhibitor that inhibits c-Met and VEGFR, also KIT, Flt-3, PDGFRβ, and Tie-2. |
| PC-45848 |
MK-2461
c-Met inhibitor
|
MK-2461 is a potent multitargeted kinase inhibitor that preferentially inhibits c-Met with IC50 of 2.5 nM, with similar potencies for Ron and Flt1 (IC50=7 and 10 nM, respectively). |
| PC-42618 |
BMS-794833
Met/VEGFR2 inhibitor
|
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7 nM/15 nM respectively. |
| PC-45530 |
AMG-337
MET inhibitor
|
AMG-337 (AMG337) is a potent and selective inhibitor of MET with biochemical IC50 of 1 nM. |
