mTOR (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-27311	DEPTOR-IN-2 DEPTOR inhibitor	DEPTOR-IN-2 (Compound 3g, Drug 3g) is a small molecule inhibitor of DEPTOR-mTOR interaction, prevents binding of recombinant DEPTOR to mTOR with IC50 of 1 uM, induces DEPTOR degradation, shows anti-myeloma cytotoxic properties.
PC-27310	NSC126405 DEPTOR inhibitor	NSC126405 is a small-molecule DEPTOR inhibitor that prevent DEPTOR binding to mTOR, acutely activates mTORC1 and selectively induces MM cell apoptosis and cell cycle arrest, binds to recombinant DEPTOR but not mTOR.
PC-27309	DEPTOR-IN-1 DEPTOR inhibitor	DEPTOR-IN-1 (Compound C3) is a small molecule putative DEPTOR inhibitor with MST KD of 9.3 uM, exhibits antimultiple myeloma activity with IC50 of 1.09 uM for RPMI 8226 cells.
PC-24226	TMBIM6 inhibitor BIA TMBIM6 inhibitor	TMBIM6 inhibitor BIA is a specific inhibitor of TMBIM6 (BAX inhibitor-1, BI-1), prevents TMBIM6 binding to mTORC2, decreases mTORC2 activity, also suppresses ER release of Ca2+ from TMBIM6, has broad anticancer activities.
PC-62011	CIDD 0067106	CIDD 0067106 is a novel natural product-based diaryloxazole that potent and selective antiproliferative activities against androgen receptor-positive breast cancer cells (MDA-MB-453 cell GI50=0.8 uM).

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