| Cat. No. |
Product Name |
Information |
| PC-43314 |
Torin1
mTOR inhibitor
|
Torin1 is a highly potent, selective inhibitor of mTORC1 and mTORC2 with IC50 of 2 and 10 nM in cell-free assays, exhibits 1,000-fold selectivity PI3K (EC50=1,800 nM). |
| PC-43029 |
Zotarolimus
FKBP ligand
|
Zotarolimus (ABT-578, A 179578) is a semi-synthetic analogue of rapamycin, inhibits FKBP-12 binding with IC50 of 2.8 nM and shows less potent systemic immunosuppression than rapamycin. |
| PC-42848 |
WYE-354
mTOR inhibitor
|
WYE-354 is a potent, selective and ATP-competitive inhibitor of mTOR with IC50 of 5 nM (recombinant mTOR ), displays >100-fold selectivity over PI3K isofoms. |
| PC-60920 |
mTOR inhibitor 10
mTOR inhibitor
|
mTOR inhibitor 10 is a potent, selective mTOR inhibitor with biochemical IC50 of 21.7 nM for mTORC1, exhibits cellular potency against mTOR with IC50 of 5 nM. |
| PC-60555 |
NV-128
mTOR inhibitor
|
NV-128 (LY-303511) is a novel isoflavone derivative that inhibits mTOR and promotes caspase-independent cell death. |
| PC-60554 |
ME-344
mTOR inhibitor
|
ME-344 is a novel mitochondrial and mTOR inhibitor with potent anti-cancer activity, inhibits leukemia cell lines with IC50 of 70-260 nM. |
| PC-60482 |
AZD3147
mTOR inhibitor
|
AZD3147 is a potent, selective dual mTORC1 and mTORC2 inhibitor with enzyme IC50 of 1.5 nM. |
| PC-60418 |
RapaLink-1
mTOR inhibitor
|
RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors. |
| PC-60132 |
Temsirolimus
mTOR inhibitor
|
Temsirolimus (CCI779, Torisel) is a rapamycin ester and mTOR inhibitor with biochemical IC50 of 1.74 uM. |
| PC-45649 |
Seco Rapamycin sodium salt
|
Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not affect mTOR.. |
| PC-45851 |
KU-0063794
mTOR inhibitor
|
KU-0063794 is a potent, specific, cell permeant inhibitor of mTOR with IC50 of 10 nM for both mTORC1 and mTORC2. |
| PC-42157 |
WYE-125132
mTOR inhibitor
|
A potent, specific, ATP-competitive and orally active mTOR inhibitor with IC50 of 0.19 nM. |
