You are here:Home-Chemical Inhibitors & Agonists-GPCR-Calcium-sensing Receptor (CaSR)

Request The Product List ofCalcium-sensing Receptor (CaSR) Calcium-sensing Receptor (CaSR)

Cat. No. Product Name Information
PC-45941

Cinacalcet

CaSR activator

Cinacalcet (AMG073) is a calcimimetic agent that acts as an allosteric activator of CaSR with EC50 of 51 nM.
PC-21722

Evocalcet

CaSR agonist

Evocalcet (MT-4580/KHK7580) is a calcimimetic agent and next-generation, oral allosteric CaSR agonist with EC50 of 93 nM (human CaSR).
PC-21721

Compound 54149

CaSR agonist

Compound 54149 is novel positive allosteric modulator (PAM) of calcium sensing receptor (CaSR) with EC50 of 41 nM.
PC-20137

(S)-AC-265347

CaSR agonist

(S)-AC-265347 is a potent, selective CaSR agonist and positive allosteric modulator (ago-PAM), 10- to 20-fold more potent than (R)-AC-265347.
PC-62910

Calindol hydrochloride

Calindol hydrochloride is a calcimimetic acting agent and positive allosteric modulator (agonist) of CaSR with EC50 of 0.31 uM (stimulated 3H IP accumulation in CHO cells at 2 mM Ca2+).
PC-45220

Strontium ranelate

A strontium(II) salt of ranelic acid that stimulates CaSR and leads to the differentiation of pre-osteoblast to osteoblast, increases the bone formation.
PC-45852

CaSR-IN-10a

A potent CaSR antagonist with IC50 of 4.4 nM in CaSR FLIPR assay..

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com