Cat. No. |
Product Name |
Information |
PC-45941 |
Cinacalcet
CaSR activator
|
Cinacalcet (AMG073) is a calcimimetic agent that acts as an allosteric activator of CaSR with EC50 of 51 nM. |
PC-21722 |
Evocalcet
CaSR agonist
|
Evocalcet (MT-4580/KHK7580) is a calcimimetic agent and next-generation, oral allosteric CaSR agonist with EC50 of 93 nM (human CaSR). |
PC-21721 |
Compound 54149
CaSR agonist
|
Compound 54149 is novel positive allosteric modulator (PAM) of calcium sensing receptor (CaSR) with EC50 of 41 nM. |
PC-20137 |
(S)-AC-265347
CaSR agonist
|
(S)-AC-265347 is a potent, selective CaSR agonist and positive allosteric modulator (ago-PAM), 10- to 20-fold more potent than (R)-AC-265347. |
PC-62910 |
Calindol hydrochloride
|
Calindol hydrochloride is a calcimimetic acting agent and positive allosteric modulator (agonist) of CaSR with EC50 of 0.31 uM (stimulated 3H IP accumulation in CHO cells at 2 mM Ca2+). |
PC-45220 |
Strontium ranelate
|
A strontium(II) salt of ranelic acid that stimulates CaSR and leads to the differentiation of pre-osteoblast to osteoblast, increases the bone formation. |
PC-45852 |
CaSR-IN-10a
|
A potent CaSR antagonist with IC50 of 4.4 nM in CaSR FLIPR assay.. |