| Cat. No. |
Product Name |
Information |
| PC-20386 |
AZD7687
DGAT1 inhibitor
|
AZD7687 (AZD-7687) is a potent, selective DGAT1 inhibitor with IC50 of 80 nM (hDGAT1), >400-fold selectivity over hACAT1. |
| PC-20385 |
AZD3988
DGAT-1 inhibitor
|
AZD3988 (AZD-3988) is a potent, selective DGAT-1 inhibitor with IC50 of 0.6/0.5/1.1 nM for human/mouse/rat DGAT-1, does not inhibit DGAT-2 at 10 uM. |
| PC-73223 |
BMS-963272
MGAT2 inhibitor
|
BMS-963272 is a potent, selective MGAT2 inhibitor with IC50 of 7.1 and 18 nM for human and mouse MAGT2, respectively. |
| PC-73119 |
PF-06427878
DGAT2 inhibitor
|
PF-06427878 is a potent, selective, oral DGAT2 inhibitor with IC50 of 99/202 nM for human/rat DGAT2, >470-fold selectivity over DGAT1 and MGAT1/2/3. |
| PC-72624 |
PF-06865571
DGAT2 inhibitor
|
PF-06865571 (Ervogastat, PF 06865571) is a potent, selective diacylglycerol acyltransferase DGAT2 inhibitor with IC50 of 17.2 and 833 nM for human and rat DGAT2, respectively. |
| PC-38095 |
PF-06424439
DGAT2 inhibitor
|
PF-06424439 (PF06424439) is a potent, selective, orally acitve DGAT2 inhibitor with IC50 of 14 nM. |
| PC-63472 |
DGAT2 inhibitor 2
DGAT2 inhibitor
|
DGAT2 inhibitor 2 is a novel potent, selective DGAT2 inhibitor with IC50 of 6 nM (hDGAT2), shows no significant activity for DGAT1 (IC50>20 uM). |
| PC-43318 |
PF-04620110
DGAT1 inhibitor
|
PF-04620110 is a potent, selective, orally bioavailable DGAT-1 inhibitor with IC50 of 19 nM, shows no acitivity for DGAT-2 (IC50>30 uM). |
| PC-43030 |
DGAT1-IN-1
DGAT1 inhibitor
|
DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM in cell-free assays. |
| PC-62951 |
JTT-553
DGAT1 inhibitor
|
JTT-553 is a novel potent, selective DGAT-1 inhibitor with IC50 of 2.38 nM, shows no inhibitory activity for human DGAT2 and ACA T1 (IC50>10 uM). |
| PC-62635 |
GSK2973980A
DGAT1 inhibitor
|
GSK2973980A is a potent and selective DGAT1 inhibitor with IC50 of 3 nM, exhibits >2,900-fold selectivity over human DGAT2, ACAT1 and ACAT2 (IC50>10 uM). |
| PC-45835 |
DGAT1-IN-4
DGAT1 inhibitor
|
DGAT1-IN-4 is a potent, selective, and orally efficacious inhibitor of DGAT-1 with IC50 of 15 nM and 9 nM for hDGAT-1 and mDGAT-1, respectively. |
