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Cat. No. Product Name Information
PC-24659

PanK inhibitor MNS

Fungal PanK inhibitor

PanK inhibitor MNS is a broad-spectrum antifungal, fungal-selective inhibitor of PanK with IC50 of 1.13 μM and 17.74 μM against CaCab1p and AfPanKp respectively, directly engages and inhibits PanK to block CoA production.
PC-24646

Tps1 inhibitor 4456dh

Fungal Tps1 inhibitor

Tps1 inhibitor 4456dh is a small molecule inhibitor of the fungal first enzyme in the trehalose biosynthesis pathway, trehalose-6-phosphate synthase (Tps1), demonstrates broad-spectrum inhibitory effects against multiple pathogenic fungal species, including Candida and Cryptococcus.
PC-23892

ISFP10

AfPGM inhibitor

ISFP10 is a specific small molecule inhibitor of A. fumigatus phosphoglucomutase (AfPGM) with IC50 of 2 uM, 50-fold selectivity over the human PGM enzyme.
PC-23890

MN-I-157

Yck2 inhibitor

MN-I-157 is a specific inhibitor of fungal casein kinase 1 (CK1) family member Yck2 with sub-micromolar potencey.
PC-23889

YK-I-02

Yck2 inhibitor

YK-I-02 is a specific inhibitor of fungal casein kinase 1 (CK1) family member Yck2 with sub-micromolar potencey, 8- to 20-fold selectivity over CK1α but less than 3-fold selectivity over p38α.
PC-23301

APX2020

Gwt1 inhibitor

APX2020 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.016-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans.
PC-23300

APX2096

Gwt1 inhibitor

APX2096 is the prodrug of APX2039, which is a novel potent small molecule inhibitor of fungal Gwt1, reduces fungal burden in vivo.
PC-23299

APX2039

Gwt1 inhibitor

APX2039 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.008-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans.
PC-23298

Manogepix

Gwt1 inhibitor

Manogepix (APX001A, E1210) is a potent antifungal agent targeting the fungal glycosylphosphatidylinositol acyltransferase Gwt1, demonstrates potent in vitro activity against clinical isolates of both Candida (Candida spp, MIC50/90=0.008/0.12 mg/L) and Aspergillus species.
PC-23185

Iodiconazole

Antifungal

Iodiconazole is a potent azole drug with strong antifungal activity (Candida albicans, MIC<0.0625 ug/mL).
PC-23074

HTS06170

Antifungal agent

HTS06170 is a small molecule inhibitor of fungal Δ(9) fatty acid desaturase, act as antivirulence agents and inhibits the invasive hyphal growth and biofilm formation of C. albicans.
PC-23073

SPB00525

Antifungal agent

SPB00525 is a small molecule inhibitor of fungal Δ(9) fatty acid desaturase (Ole1), act as antivirulence agents and inhibits the invasive hyphal growth and biofilm formation of C. albicans.

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