| Cat. No. |
Product Name |
Information |
| PC-23301 |
APX2020
Gwt1 inhibitor
|
APX2020 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.016-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans. |
| PC-23300 |
APX2096
Gwt1 inhibitor
|
APX2096 is the prodrug of APX2039, which is a novel potent small molecule inhibitor of fungal Gwt1, reduces fungal burden in vivo. |
| PC-23299 |
APX2039
Gwt1 inhibitor
|
APX2039 is a novel potent small molecule inhibitor of fungal Gwt1, has MIC of 0.008-0.031 ug/ mL against C. neoformans, C. gattii, Candida albicans. |
| PC-23298 |
Manogepix
Gwt1 inhibitor
|
Manogepix (APX001A, E1210) is a potent antifungal agent targeting the fungal glycosylphosphatidylinositol acyltransferase Gwt1, demonstrates potent in vitro activity against clinical isolates of both Candida (Candida spp, MIC50/90=0.008/0.12 mg/L) and Aspergillus species. |
| PC-23185 |
Iodiconazole
Antifungal
|
Iodiconazole is a potent azole drug with strong antifungal activity (Candida albicans, MIC<0.0625 ug/mL). |
| PC-23074 |
HTS06170
Antifungal agent
|
HTS06170 is a small molecule inhibitor of fungal Δ(9) fatty acid desaturase, act as antivirulence agents and inhibits the invasive hyphal growth and biofilm formation of C. albicans. |
| PC-23073 |
SPB00525
Antifungal agent
|
SPB00525 is a small molecule inhibitor of fungal Δ(9) fatty acid desaturase (Ole1), act as antivirulence agents and inhibits the invasive hyphal growth and biofilm formation of C. albicans. |
| PC-60411 |
SCY-078
Fungal 1,3-β-glucan synthase inhibitor
|
Ibrexafungerp (MK 3118, SCY-078) is a novel orally bioavailable fungal beta-1,3-D glucan synthetase inhibitor against Candida species C. glabrata (MIC 0.03 to 0.25 ug/ml), C. parapsilosis (MIC 0.06 to 0.25 ug/ml). |
| PC-22726 |
Ibrexafungerp citrate
Fungal 1,3-β-glucan synthase inhibitor
|
Ibrexafungerp (MK 3118, SCY-078) citrate is a novel orally bioavailable fungal beta-1,3-D glucan synthetase inhibitor against Candida species C. glabrata (MIC 0.03 to 0.25 ug/ml), C. parapsilosis (MIC 0.06 to 0.25 ug/ml). |
| PC-22712 |
MBX-7591
Antifungal agent
|
MBX-7591 is a nonspirocyclic piperidine antifungal agent with MIC of 1.2 uM for A. fumigatus, shows promising antifungal activity against Aspergillus fumigatus and other pathogenic fungi, including strains resistant to triazoles. |
| PC-22140 |
Albaconazole
Antifungal agent
|
Albaconazole (UR-9825) is a broad-spectrum triazole antifungal agent with MIC of 30 nM against protozoan parasite Trypanosoma (Schizotrypanum) cruzi. |
| PC-22136 |
Tetrazole compound D2
Antifungal agent
|
Tetrazole compound D2 is a novel antifungal inhibitor with MIC values of <0.008, <0.008, and 2 μg/mL against Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus, respectively. |
