| Cat. No. |
Product Name |
Information |
| PC-27951 |
Isoconazole
Antifungal
|
Isoconazole is a broad-spectrum imidazole antifungal agent highly effective against a wide range of fungi, inhibits lanosterol 14α-demethylase, a key enzyme in the ergosterol synthesis pathway. |
| PC-27950 |
Terconazole
Antifungal
|
Terconazole (R42470) is an azole antifungal agent that inhibits ergosterol biosynthesis via specifically targets fungal lanosterol 14α-demethylase (CYP51A1). |
| PC-27949 |
Bifonazole
Antifungal
|
Bifonazole (Bay H-4502) is an imidazole antifungal agent that inhibits ergosterol biosynthesis via specifically targets fungal lanosterol 14α-demethylase (CYP51A1), also is a SARS-CoV-2 blocking agent that binds ACE2 and prevents association with the RBD, affecting entry and replication of spike-pseudotyped viruses as well as native SARS-CoV-2 and its variants of concern (VOCs). |
| PC-27948 |
Miconazole nitrate
Antifungal
|
Miconazole nitrate (R18134) is an imidazole antifungal agent, targets the enzyme 14 demethylase and inhibits biosynthesis of ergosterol in common fungal pathogens, also significantly reduces prostate cancer cell viability, clonogenic growth, invasion and migration, targets MCL-1 to exert an anti-leukemic effect, exhibits anti-tumor properties against multiple cancer types. |
| PC-27947 |
Miconazole
Antifungal
|
Miconazole (R18134) is an imidazole antifungal agent, targets the enzyme 14 demethylase and inhibits biosynthesis of ergosterol in common fungal pathogens, also significantly reduces prostate cancer cell viability, clonogenic growth, invasion and migration, targets MCL-1 to exert an anti-leukemic effect, exhibits anti-tumor properties against multiple cancer types. |
| PC-27946 |
Sulconazole
Antifungal
|
Sulconazole is an imidazole derivative broad-spectrum fungicide with activity against dermatophytes and yeasts, and some gram-positive bacteria, including Staphylococcus aureus, S epidermidis, and Streptococcus faecalis, inhibits the enzyme 14 demethylase, impairing the biosynthesis of ergosterol, which is essential for fungal cell wall synthesis. |
| PC-27945 |
Sulconazole mononitrate
Antifungal
|
Sulconazole mononitrate is an imidazole derivative broad-spectrum fungicide with activity against dermatophytes and yeasts, and some gram-positive bacteria, including Staphylococcus aureus, S epidermidis, and Streptococcus faecalis, inhibits the enzyme 14 demethylase, impairing the biosynthesis of ergosterol, which is essential for fungal cell wall synthesis. |
| PC-27944 |
Oxiconazole nitrate
Antifungal
|
Oxiconazole nitrate (Sgd 301-76) is a broad spectrum antifungal agent, shows fungicidal activity of for Aspergillus fumigatus, Cryptococcus neoformans, Candida albicans and Trichophyton mentagrophytes, also is a highly efficacious activator of CYP3A4 transactivation, exhibits certain anti-tumor effect against CRC via PRDX2-mediated autophagy arrest. |
| PC-27943 |
Tioconazole
Antifungal
|
Tioconazole (UK-20,349) is an antifungal imidazole derivative with activity against Candida spp., Torulopsis glabrata, Cryptococcus neoformans, Aspergillus spp., and dermatophyte fungi (Trichophyton spp. and Microsporum spp.). with MIC of 0.06-1.0 ug/mL. |
| PC-27941 |
Butoconazole nitrate
Antifungal
|
Butoconazole nitrate is an azole antifungal of the imidazole class, directly targets and inhibits lanosterol 14α-demethylase. |
| PC-27940 |
Butoconazole
Antifungal
|
Butoconazole is an azole antifungal of the imidazole class, directly targets and inhibits lanosterol 14α-demethylase. |
| PC-27773 |
TAK-456
Antifungal
|
TAK-456 is an oral triazole with potent and broad-spectrum in vitro antifungal activity shows MIC90 of 0.25 ug/mL against clinical isolates of Candida spp., Aspergillus spp., and Cryptococcus neoformans, except for Candida glabrata. |
