| Cat. No. |
Product Name |
Information |
| PC-60411 |
SCY-078
Fungal 1,3-β-glucan synthase inhibitor
|
Ibrexafungerp (MK 3118, SCY-078) is a novel orally bioavailable fungal beta-1,3-D glucan synthetase inhibitor against Candida species C. glabrata (MIC 0.03 to 0.25 ug/ml), C. parapsilosis (MIC 0.06 to 0.25 ug/ml). |
| PC-45366 |
Micafungin
|
Micafungin is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase, inhibits the production of 1,3-β-D-glucan in fungal cell walls, acts as a neddylation inhibitor that targets Ubiquitin-conjugating enzyme 2M (UBE2M). |
| PC-42761 |
AN-2690
LeuRS inhibitor
|
AN-2690 (Tavaborole) is an antifungal compound that inhibits cytoplasmic leucyl-tRNA synthetase (LeuRS) for the potential treatment of nnychomycosis. |
| PC-45196 |
Posaconazole hydrate
Antifungal
|
Posaconazole hydrate is a triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors, more potent at inhibiting 14α-demethylase than itraconazole. |
| PC-45195 |
Posaconazole
Antifungal
|
Posaconazole is a triazole antifungal agent that blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase and accumulation of methylated sterol precursors, more potent at inhibiting 14α-demethylase than itraconazole. |
| PC-45319 |
Itraconazole
Hedgehog inhibitor, C1GALT1 inhibitor
|
Itraconazole (R51211) is a triazole antifungal agent for fungal infections via inhibition of lanosterol 14α-demethylase, inhibits hedgehog signaling pathway with IC50 of 800 nM. |
| PC-45964 |
Voriconazole
Fungal 14α-demethylase inhibitor
|
Voriconazole (UK109496) is a triazole antifungal agent that acts as a 14α-demethylase inhibitor. |
| PC-22712 |
MBX-7591
Antifungal agent
|
MBX-7591 is a nonspirocyclic piperidine antifungal agent with MIC of 1.2 uM for A. fumigatus, shows promising antifungal activity against Aspergillus fumigatus and other pathogenic fungi, including strains resistant to triazoles. |
| PC-22140 |
Albaconazole
Antifungal agent
|
Albaconazole (UR-9825) is a broad-spectrum triazole antifungal agent with MIC of 30 nM against protozoan parasite Trypanosoma (Schizotrypanum) cruzi. |
| PC-22136 |
Tetrazole compound D2
Antifungal agent
|
Tetrazole compound D2 is a novel antifungal inhibitor with MIC values of <0.008, <0.008, and 2 μg/mL against Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus, respectively. |
| PC-21530 |
Phenamacril
Myosin 5 inhibitor
|
Phenamacril (Fungicide JS399-19) is a specific inhibitor of myosin5 protein (Myo5), inhibits ergosterol biosynthesis pathway and exhibits strong inhibitory effects on both carbendazim-resistant and phenamacril-resistant isolates. |
| PC-21256 |
CWHM-974
Antifungal
|
CWHM-974 is a fluphenazine derivative with antifungal activity against Candida albicans, significantly reduces susceptibility to multidrug transporter-mediated resistance. |
