| Cat. No. |
Product Name |
Information |
| PC-20495 |
PF-6870961
Ghrelin receptor inverse agonist
|
PF-6870961 is a major hydroxy metabolite of the novel ghrelin receptor (GHSR) inverse agonist PF-5190457. |
| PC-38623 |
Capromorelin
Ghrelin receptor agonist
|
Capromorelin (CP-424391) is a pyrazolinone-piperidine dipeptide growth hormone secretagogue and ghrelin receptor agonist with Ki value of 7 nM (hGHS-R1a), and EC50 vaule of 3 nM (rat pituicyte). |
| PC-72842 |
N8279
GHSR1a agonist
|
N8279 (NCATS-SM8864) is a selective, brain-penetrant small molecule Gαq-biased GHSR1a agonist with binding IC50 of 1.3 uM. |
| PC-72816 |
KARI 201
GHSR agonist
|
KARI 201 (KARI-201) is a dual-action small molecule that exhibit highly selective inhibition effects on Acid sphingomyelinase (ASM), and act as a ghrelin receptor agonist. |
| PC-35623 |
Ghrelin agonist HM01
GHSR agonist
|
Ghrelin agonist HM01 is a novel potent, orally available ghrelin (GHS-R) agonist with Ki of 1.42 nM (human GHS-R1a), induces potent activation of intracellular calcium signaling with EC50 of 1.25 nM. |
| PC-62603 |
Z-505 hydrochloride
Ghrelin agonist
|
Z-505 hydrochloride is a novel, orally active ghrelin (GHSR1a) agonist with EC50 of 2.08 nM and 5.46 nM for rat and mouse GHSR1a, respectively. |
| PC-61828 |
JMV 2959
Ghrelin agonist
|
JMV 2959 (AEZS-123) is a potent ghrelin receptor (GHS-R1A) antaognist with binding IC50 of 32 nM. |
| PC-61386 |
Livoletide
GHSR agonist
|
Livoletide (AZP-531) is the first-in-class analogue of unacylated ghrelin, and unacylated ghrelin receptor (GHS-R) agonist. |
| PC-61098 |
PF-05190457
GHSR inverse agonist
|
PF-05190457 (PF-5190457) is a potent, selective, and orally bioavailable ghrelin receptor (GHSR) inverse agonist with binding pKi of 8.36. |
| PC-47503 |
Alexamorelin
GHSR agonist
|
Alexamorelin is a synthetic growth hormone (GH) secretagogue, and agonist of the growth hormone secretagogue receptor (GHS-R). |
| PC-45866 |
Ibutamoren mesylate
GHSR agonist
|
Ibutamoren mesylate (MK-0677) is a non-peptidic, poten and selective, orally-active agonist of the ghrelin receptor (GHSR) with EC50 of 1.3 nM (releases GH from rat pituitary cells). |
| PC-44045 |
Anamorelin fumarate
GHSR agonist
|
Anamorelin fumarate (RC-1291, ONO-7643) is a non-peptide, centrally-penetrant and selective agonist of GHSR with 50 of 0.74 nM, shows appetite-enhancing and anabolic effects, orally bioactive. |
