| Cat. No. |
Product Name |
Information |
| PC-45163 |
Alcaftadine
Histamine H1 antagonist
|
Alcaftadine (R-89674) is a H1 histamine receptor antagonist that used for prevention of allergic conjunctivitis, has a high affinity for histamine H1 and H2 receptors and a lower affinity for H4 receptors. |
| PC-45251 |
Tripelennamine hydrochloride
H1 receptor antagonist
|
Tripelennamine hydrochloride (Pyribenzamine hydrochloride) is the first-generation antihistamine that acts primarily as H1 receptor antagonist. |
| PC-28139 |
GD136 hydrochloride
H1R/H4R antagonist
|
GD136 hydrochloride (VUF10775, GD-136) is a potent, selective dual histamine H1 and H4 receptors (H1R/H4R) ligand / antagonist with pKi of 7.61 and 7.93 (hH1R/hH4R), shows >100-fold selectivity over hH2R and hH3R. |
| PC-27866 |
LINS01022
H3R antagonist
|
LINS01022 is a high affinity, selective histamine H3 receptor (H3R) antagonist with pKi of 8.2, >1000-fold selective over H4R, exhibits potent antiproliferative effect against 4T1 and MDA-MB-231 TNBC cell lines. |
| PC-27477 |
GSK189254
H3R antagonist
|
GSK189254 (GSK189254A hydrochloride) is a potent, selective histamine H3 receptor (H3R) antagonist with pKi of 9.59 -9.90 and 8.51-9.17 for human and rat H3R respectively. |
| PC-27476 |
GSK189254A
H3R antagonist
|
GSK189254A (GSK189254 free base) is a potent, selective histamine H3 receptor (H3R) antagonist with pKi of 9.59 -9.90 and 8.51-9.17 for human and rat H3R respectively. |
| PC-27475 |
GSK207040
H3R antagonist
|
GSK207040 is a potent, selective histamine H3 receptor (H3R) antagonist with pKi of 9.67 and 9.08 for human and rat H3 receptors respectively. |
| PC-27473 |
GSK334429
H3R antagonist
|
GSK334429 is a potent, selective histamine H3 receptor (H3R) antagonist with pKi of 9.49 and 9.12 for human and rat H3 receptors respectively. |
| PC-26776 |
Fexofenadine
H1 receptor antagonist, ADAM17 inhibitor
|
Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist, also binds and inhibits the catalytic activity of human ADAM17, shows anti-inflammatory effects. |
| PC-26243 |
Thioperamide
H3R antagonist
|
Thioperamide (MR-12842) is a potent, selective, orally available, brain penetrant inverse agonist / antagonist of histamine H3-receptor (H3R) with Ki of 4.3 nM for inhibition of [3H]histamine release, inhibits [3H]histamine synthesis of KI of 31 nM. |
| PC-26036 |
BP1.3656B
H3R antagonist
|
BP1.3656B is a highly potent and selective histamine H3 receptor (H3R) inverse agonist/antagonist with IC50 of 0.38 nM. |
| PC-24402 |
Promethazine hydrochloride
Histamine antagonist
|
Promethazine hydrochloride is an orally active histamine receptor antagonist, shows antihistaminic (H1), sedative, antiemetic, anticholinergic, and antimotion sickness properties. |
