| Cat. No. |
Product Name |
Information |
| PC-26243 |
Thioperamide
H3R antagonist
|
Thioperamide (MR-12842) is a potent, selective, orally available, brain penetrant inverse agonist / antagonist of histamine H3-receptor (H3R) with Ki of 4.3 nM for inhibition of [3H]histamine release, inhibits [3H]histamine synthesis of KI of 31 nM. |
| PC-26036 |
BP1.3656B
H3R antagonist
|
BP1.3656B is a highly potent and selective histamine H3 receptor (H3R) inverse agonist/antagonist with IC50 of 0.38 nM. |
| PC-24402 |
Promethazine hydrochloride
Histamine antagonist
|
Promethazine hydrochloride is an orally active histamine receptor antagonist, shows antihistaminic (H1), sedative, antiemetic, anticholinergic, and antimotion sickness properties. |
| PC-23593 |
ADS1017 trihydrochloride
H3R antagonist
|
ADS1017 trihydrochloride is a potent, selective histamine H3 receptor antagonist with pKi of 7.9/6.8 for rH3R/hH3R in radioligand binding assays respectively, 20-fold selective over H4R. |
| PC-23592 |
ADS1017
H3R antagonist
|
ADS1017 is a potent, selective histamine H3 receptor antagonist with pKi of 7.9/6.8 for rH3R/hH3R in radioligand binding assays respectively, 20-fold selective over H4R. |
| PC-23507 |
Latrepirdine dihydrochloride
97657-92-6
|
Latrepirdine dihydrochloride (Dimebolin, Dimebone) is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors, stimulates amyloid precursor protein (APP) catabolism and amyloid-β (Aβ) secretion. |
| PC-23506 |
Latrepirdine
3613-73-8
|
Latrepirdine (Dimebolin, Dimebone) is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors, stimulates amyloid precursor protein (APP) catabolism and amyloid-β (Aβ) secretion. |
| PC-23486 |
Ketotifen
PDE8B inhibitor
|
Ketotifen (HC 20-511) is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer, also is a PDE8B inhibitor. |
| PC-23473 |
JNJ-7777120
H4R antagonist
|
JNJ-7777120 (JNJ 7777120) is potent and selective histamine H4 receptor (H4R) antagonist with Ki of 4.5 nM (hH4R), >1000-fold selectivity over H1, H2, or H3 receptors. |
| PC-23262 |
Izuforant
H4R antagonist
|
Izuforant (JW1601, LEO 152020) is a potent, selective and oral histamine 4 receptor (H4R) antagonist with IC50 of 65.1-72.2 nM in human whole-blood assay, and pKi of 6.83 and 5.36 at mouse and rat histamine receptor subtypes. shows lower pKi values against other histamine receptor. |
| PC-42910 |
Pitolisant oxalate
|
A potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM. |
