| Cat. No. |
Product Name |
Information |
| PC-63413 |
JNJ-28610244
Histamine H4 agonist
|
JNJ-28610244 is a potent, selective agonist of histamine H4 receptor (H4R) with pKi of 7.3 and pEC50 of 7.0 respectively, |
| PC-63410 |
JNJ-28307474
Histamine H4 antagonist
|
JNJ-28307474 is a potent, selective antagonist of the histamine H4 receptor (H4R), inhibits LPS-induced TNF production. |
| PC-63399 |
Toreforant
Histamine H4 antagonist
|
Toreforant (JNJ-38518168) is a potent, selective histamine H4 receptor (H4R) antagonist with Ki of 8.4 nM, shows excellent selectivity over other receptors including the other histamine receptors. |
| PC-63035 |
MK-0249
Histamine H3 antagonist
|
MK-0249 is a potent, selective and orally active histamine H3 receptor antagonist, with an IC50 of 1.7 nM for human H3. |
| PC-63034 |
PF-03654746
Histamine H3 antagonist
|
PF-03654746 (PF-3654746) is a potent, selective, orally bioactive antagonist of H3 receptor with Ki of 2.3 nM. |
| PC-63033 |
PF-03654764
Histamine H3 antagonist
|
PF-03654764 (PF-3654764) is a potent, selective, orally bioactive antagonist of H3 receptor with Ki of 1.4 nM. |
| PC-63032 |
ABT-288
Histamine H3 antagonist
|
ABT-288 is a potent, selective and competitive antagonist of H3 receptor with Ki of 1.9/8.2 nM for human/rat H3 respectively. |
| PC-61996 |
LY2624803
H1R/5-HT2A modulator
|
LY2624803 is a novel potent histamine H1 and 5-HT2A receptor modulator in the pipeline for treating insomnia. |
| PC-61663 |
JNJ-10181457 dihydrochloride
Histamine H3 antagonist
|
JNJ-10181457 dihydrochloride is a neutral, potent and selective, brain penetrant H3 antagonist with pKi of 8.93, pA2 of 9.22 for hH3. |
| PC-61662 |
JNJ-10181457
Histamine H3 antagonist
|
JNJ-10181457 is a neutral, potent and selective, brain penetrant H3 antagonist with pKi of 8.93, pA2 of 9.22 for hH3. |
| PC-61661 |
JNJ-39220675
Histamine H3 antagonist
|
JNJ-39220675 is potent and selective, brain penetrant H3 antagonist with Ki of 1.4 nM, pA2 of 9.42 for hH3. |
| PC-61616 |
Irdabisant hydrochloride
H3 receptor antagonist
|
Irdabisant (CEP-26401) hydrochloride is a potent, selective, orally active histamine H3 receptor antagonist with Ki of 2 nM and 7 nM for human and rat H3Rs, respectivity. |
