| Cat. No. |
Product Name |
Information |
| PC-43332 |
CC-401 hydrochloride
JNK inhibitor
|
CC-401 hydrochloride is a potent, selective, ATP-competitive pan-JNK inhibitor with Ki of 25-50 nM, displays >40-fold selectivity over other related kinases, including p38, ERK, IKK2, PK C, Lck, and ZAP70. |
| PC-43238 |
SR-3306
JNK inhibitor
|
SR-3306 (SR3306) is a highly selective, brain penetrant, potent inhibitor of JNK with IC50 of 67, 283 and 159 nM for JNK1, JNK2 and JNK3, >100-fold selectivity over p38. |
| PC-63199 |
CC-401
JNK inhibitor
|
CC-401 (JNK-401) is a potent, selective, ATP-competitive pan-JNK inhibitor with Ki of 25-50 nM, displays >40-fold selectivity over other related kinases. |
| PC-42856 |
SP600125
JNK inhibitor, NQO1 inhibitor
|
SP600125 is a potent, selective, reversible, ATP-competitive inhibitor of JNK with IC50 of 40, 40 and 90 nM for JNK1, JNK2 and JNK3, respectively. |
| PC-42552 |
BI-78D3
JNK inhibitor
|
BI-78D3 is a small molecule JIP1 mimic that functions as substrate competitive inhibitor of JNK with IC50 of 500 nM. |
| PC-42095 |
IQ-1S
JNK inhibitor
|
IQ-1S is a potent, highly specific JNK inhibitor with IC50 of 390, 360, and 87 nM for JNK1, JNK2, and JNK3, respectively. |
| PC-42785 |
AS601245
JNK inhibitor
|
AS601245 (AS-601245) is a potent and selective inhibitor of JNK with IC50s of 70/220/150 nM for JNK1/2/3 respectively. |
| PC-47480 |
AM-111
JNK inhibitor
|
Brimapitide (KU002, D-JNKI-1, XG-102, AM-111) is a cell-permeable peptide inhibitor of JNK kinases. |
| PC-27652 |
JNK2 inhibitor J27
JNK2 inhibitor
|
JNK2 inhibitor J27 (JNK2-IN-1) is a selective c-Jun N-terminal kinase 2 (JNK2) inhibitor with Kd of 79.2 uM, decreases the release of TNF-α and IL-6 in mouse and human cells J774A.1 and THP-1 (IL-6, IC50=0.22 μM) through NF-κB/MAPK pathway. |
| PC-26259 |
JNK3 inhibitor 15g
JNK3 inhibitor
|
JNK3 inhibitor 15g is a potent, isoform-selective JNK3 inhibitor with IC50 of 4.1 nM, 10-fold and 30-fold selective over JNK1 or JNK2. |
| PC-26258 |
JNK3 inhibitor 15d
JNK3 inhibitor
|
JNK3 inhibitor 15d is a potent, isoform-selective JNK3 inhibitor with IC50 of 1.0 nM, <100-fold selective over JNK1 or JNK2. |
| PC-26257 |
JNK3 inhibitor 29
JNK3 inhibitor
|
JNK3 inhibitor 29 is a potent, selective c-Jun N-terminal kinase 3 (JNK3) with IC50 of 5 nM, 15-fold and 75-fold selective over JNK2 and JNK1. |
