| Cat. No. |
Product Name |
Information |
| PC-45411 |
LPA2 antagonist 1
LPA2 antagonist
|
LPA2 antagonist 1 is a potent, selective LPA2 (EDG4) antagonist with IC50 of 17 nM. |
| PC-42950 |
Ozanimod
S1P1/S1P5 agonist
|
Ozanimod (RPC-1063) is a potent, selective agonist of S1P1 and S1P5 receptor with EC50 of 0.41 nM and 11 nM respectively. |
| PC-42341 |
Icanbelimod
S1PR agonist
|
Icanbelimod (CBP-307) is a highly potent, next-generation highly potent sphingosine-1-phosphate receptor (S1PR) agonist with EC50 of 3.55 nM (S1PR1), specifically targets S1PR1/4/5. |
| PC-45386 |
Cenerimod
S1P1 agonist
|
Cenerimod (ACT-334441) is a potent and orally available S1P1 receptor agonist with EC50 of 2.7 nM. |
| PC-45066 |
Amiselimod hydrochloride
S1P1 modulator
|
Amiselimod (MT-1303) hydrochloride is a prodrug S1P1 receptor modulator lacking S1P3 receptor agonism to avoid bradycardia associated with fingolimod and other S1P receptor modulators. |
| PC-42284 |
ONO-7300243
LPA1 inhibitor
|
ONO7300243 is a novel potent, selective, orally available lysophosphatidic acid receptor 1 (LPA1) antagonist with IC50 of 0.16 uM. |
| PC-42379 |
CYM-5541
S1P3 agonist
|
CYM-5541 (ML249) is a potent, selective, allosteric and full agonist of S1P3 receptor with EC50 of 72-132 nM. |
| PC-26330 |
Ibrilparant
LPAR1/LPA1 antagonist
|
Ibrilparant is a potent, selective, and orally active lysophosphatidic acid receptor subtype 1 receptor (LPA1 receptor, LPAR1) antagonist. |
| PC-26262 |
CAY10444
S1P3 antagonist
|
CAY10444 (BML-241) is a selective S1P3 receptor antagonist, inhibits S1P-induced calcium mobilization in CHO cells expressing human S1P3 with IC50 of 11.6 uM. |
| PC-25483 |
BMS-986104
S1PR1 modulator
|
BMS-986104 is a potent, selective S1P1 receptor (S1PR1) modulator. |
| PC-24539 |
LPA1 antagonist Compound A
LPA1 antagonist
|
LPA1 antagonist Compound A is a potent, selective, and brain penetrant lysophosphatidic acid receptor 1 (LPA1) antagonist with IC50 of 18.8 nM in 35S-GTPγS binding assays, and IC50 of 12.03 nM in Ca2+ influx assays. |
| PC-24186 |
Sumonerimod
S1P1 agonist
|
Sumonerimod is a potent, selective S1P1 agonist. |
