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Cat. No. Product Name Information
PC-60014

PF-06260933

MAP4K4 inhibitor

PF-06260933 (PF06260933,PF6260933) is a potent, selective, orally available MAP4K4 inhibitor with IC50 of 3.7 nM.
PC-42105

GNE-495

MAP4K4 inhibitor

GNE-495 (GNE495) is a potent and highly selective, cell permeable MAP4K4 inhibitor with IC50 of 3.7 nM.
PC-25408

TK-850

TGF-βR1/MAP4K4

TK-850 is a potent, dual inhibitor of transforming growth factor-β receptor 1 (TGF-βRI, TGFBR1) and mitogen-activated protein 4 kinase 4 (MAP4K4) with binding Kd of 4.5 nM and 1.4 nM respectively.
PC-22569

HPK1-IN-3

HPK1 inhibitor

HPK1-IN-3 is a potent, selective, ATP-competitive hematopoietic progenitor kinase 1 (HPK1, MAP4K1) inhibitor with IC50 of 0.25 nM in TR-FRET assays.
PC-22568

KHK-6

HPK1 inhibitor

KHK-6 is a potent, selective, ATP-competitive inhibitor of serine/threonine kinase hematopoietic progenitor kinase 1 (HPK1, MAP4K1) with IC50 of 20 nM.

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