| Cat. No. |
Product Name |
Information |
| PC-60014 |
PF-06260933
MAP4K4 inhibitor
|
PF-06260933 (PF06260933,PF6260933) is a potent, selective, orally available MAP4K4 inhibitor with IC50 of 3.7 nM. |
| PC-42105 |
GNE-495
MAP4K4 inhibitor
|
GNE-495 (GNE495) is a potent and highly selective, cell permeable MAP4K4 inhibitor with IC50 of 3.7 nM. |
| PC-25408 |
TK-850
TGF-βR1/MAP4K4
|
TK-850 is a potent, dual inhibitor of transforming growth factor-β receptor 1 (TGF-βRI, TGFBR1) and mitogen-activated protein 4 kinase 4 (MAP4K4) with binding Kd of 4.5 nM and 1.4 nM respectively. |
| PC-22569 |
HPK1-IN-3
HPK1 inhibitor
|
HPK1-IN-3 is a potent, selective, ATP-competitive hematopoietic progenitor kinase 1 (HPK1, MAP4K1) inhibitor with IC50 of 0.25 nM in TR-FRET assays. |
| PC-22568 |
KHK-6
HPK1 inhibitor
|
KHK-6 is a potent, selective, ATP-competitive inhibitor of serine/threonine kinase hematopoietic progenitor kinase 1 (HPK1, MAP4K1) with IC50 of 20 nM. |