| Cat. No. |
Product Name |
Information |
| PC-42266 |
Triapine
RRM2 inhibitor
|
Triapine (3-AP, PAN-811, OCX191, NSC 663249) is a potent inhibitor of ribonucleotide reductase subunit M2 (RRM2) with broad spectrum antitumor activity. |
| PC-42285 |
Acelarin
|
Acelarin (NUC-1031, CPF-31) is a gemcitabine phosphoramidate prodrug that can overcome the key cancer resistance |
| PC-45223 |
Tegafur
|
A chemotherapeutic prodrug of 5-flourouracil (5-FU) used in the treatment of cancers. |
| PC-42672 |
5-Azacytidine
|
5-Azacytidine (5-AzaC, Azacitidine) is a chemical analog of Cytidine that inhibits DNA methyltransferase, induces mitochondrial apoptosis and autophagy. |
| PC-26703 |
PSB-24379
CD39 inhibitor
|
PSB-24379 is a potent, selective inhibitor of ATP-hydrolyzing ectoenzyme nucleoside triphosphate diphosphohydrolase-1 (NTPDase1, CD39) with Ki of 77.4 nM, shows ancillary CD73 inhibition with Ki of 240 nM. |
| PC-26077 |
MSD-914
ACHY inhibitor
|
MSD-914 is a potent, selective S-adenosylhomocysteine hydrolase (AHCY) inhibitor with IC50 of 40 nM, shows broad-spectrum in vitro anti-filovirus activity against EBOV, Marburg virus, and Sudan ebolavirus. |
| PC-24830 |
N3PT
Transketolase inhibitor
|
N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor, N3PT is pyrophosphorylated and then binds to transketolase with Kd of 22 nM. |
| PC-24757 |
POM-1
CD39 inhibitor
|
POM-1 (Sodium metatungstate, Sodium polyoxotungstate) is an effective NTPDase inhibitor with Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1 (CD39), NTPDase 3 and NTPDase 2 respectively, inhibits ATP breakdown and shows anti-inflammatory and anti-cancer effect. |
| PC-22737 |
Azathioprine
Purine synthesis inhibitor
|
Azathioprine (BW 57-322) is a purine synthesis inhibitor and orally active immunosuppressive agent. |
| PC-22531 |
OR0642
dCK inhibitor
|
OR0642 is a highly potent, specific deoxycytidine kinase (dCK) inhibitor with IC50 of 2.2 nM. |
| PC-22447 |
L-Isoleucine
Nucleoside analog
|
L-isoleucine is the L-enantiomer of isoleucine, has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. |
| PC-22379 |
5-Fluorocytosine
Nucleoside analog
|
5-Fluorocytosine (Flucytosine) is an organofluorine compound and antifungal agent, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida, neoplasm infection, as well as anticaner acitvities. |
