Cat. No. |
Product Name |
Information |
PC-42672 |
5-Azacytidine
|
5-Azacytidine (5-AzaC, Azacitidine) is a chemical analog of Cytidine that inhibits DNA methyltransferase, induces mitochondrial apoptosis and autophagy. |
PC-24757 |
POM-1
CD39 inhibitor
|
POM-1 (Sodium metatungstate, Sodium polyoxotungstate) is an effective NTPDase inhibitor with Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1 (CD39), NTPDase 3 and NTPDase 2 respectively, inhibits ATP breakdown and shows anti-inflammatory and anti-cancer effect. |
PC-24716 |
PAICS inhibitor RLK
PAICS inhibitor
|
PAICS inhibitor RLK is a specific, small molecule inhibitor of PAICS, an enzyme involved in de novo purine biosynthesis. |
PC-22737 |
Azathioprine
Purine synthesis inhibitor
|
Azathioprine (BW 57-322) is a purine synthesis inhibitor and orally active immunosuppressive agent. |
PC-22531 |
OR0642
dCK inhibitor
|
OR0642 is a highly potent, specific deoxycytidine kinase (dCK) inhibitor with IC50 of 2.2 nM. |
PC-22447 |
L-Isoleucine
Nucleoside analog
|
L-isoleucine is the L-enantiomer of isoleucine, has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. |
PC-22379 |
5-Fluorocytosine
Nucleoside analog
|
5-Fluorocytosine (Flucytosine) is an organofluorine compound and antifungal agent, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida, neoplasm infection, as well as anticaner acitvities. |
PC-21771 |
TH7528
SAMHD1 inhibitor
|
TH7528 (TH-7528) is a specific small-molecule inhibitor against the dNTP triphosphohydrolase (dNTPase) SAMHD1, inhibits the enzymatic activities of SAMHD1 against dGTP, Cl-F-ara-ATP, and ara-CTP with IC50 of 4.5, 2.8 and 2.6 uM, respectively. |
PC-72499 |
N6-benzyladenosine
DNPH1 inhibitor
|
N6-benzyladenosine (DNPH1i, N6-benzyl-AMP) is a nucleoside analog that acts as competitive inhibitor of deoxynucleotide N-hydrolase DNPH1. |
PC-72483 |
MRT00252040
PAICS inhibitor
|
MRT00252040 (PAICSi) is a small molecule inhibitor PAICS, which catalyzes two steps in the de novo purine synthesis pathway. |
PC-36085 |
Aspacytarabine
|
Aspacytarabine (Astarabine, BST236) is a cytarabine conjugate that shows anti-neoplastic agents for inhibiting cancer cell growth. . |
PC-35560 |
Elacytarabine
|
Elacytarabine (CP-4055, CP4055, ELACYT) is a fatty acid derivative of cytarabine with potential antineoplastic activity. |