| Cat. No. |
Product Name |
Information |
| PC-42285 |
Acelarin
|
Acelarin (NUC-1031, CPF-31) is a gemcitabine phosphoramidate prodrug that can overcome the key cancer resistance |
| PC-45223 |
Tegafur
|
A chemotherapeutic prodrug of 5-flourouracil (5-FU) used in the treatment of cancers. |
| PC-42672 |
5-Azacytidine
|
5-Azacytidine (5-AzaC, Azacitidine) is a chemical analog of Cytidine that inhibits DNA methyltransferase, induces mitochondrial apoptosis and autophagy. |
| PC-25695 |
DNPH1 inhibitor 38
DNPH1 inhibitor
|
DNPH1 inhibitor 38 is a potent, non-nucleoside inhibitor of 2′-Deoxynucleoside 5′-monophosphate glycosidase (DNPH1, RCL) with binding pIC50 of 9.3, inhibits the hydrolysis of hmdUMP catalyzed by DNPH1 with pIC50 of 9.3. |
| PC-24830 |
N3PT
Transketolase inhibitor
|
N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor, N3PT is pyrophosphorylated and then binds to transketolase with Kd of 22 nM. |
| PC-24757 |
POM-1
CD39 inhibitor
|
POM-1 (Sodium metatungstate, Sodium polyoxotungstate) is an effective NTPDase inhibitor with Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1 (CD39), NTPDase 3 and NTPDase 2 respectively, inhibits ATP breakdown and shows anti-inflammatory and anti-cancer effect. |
| PC-22737 |
Azathioprine
Purine synthesis inhibitor
|
Azathioprine (BW 57-322) is a purine synthesis inhibitor and orally active immunosuppressive agent. |
| PC-22531 |
OR0642
dCK inhibitor
|
OR0642 is a highly potent, specific deoxycytidine kinase (dCK) inhibitor with IC50 of 2.2 nM. |
| PC-22447 |
L-Isoleucine
Nucleoside analog
|
L-isoleucine is the L-enantiomer of isoleucine, has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. |
| PC-22379 |
5-Fluorocytosine
Nucleoside analog
|
5-Fluorocytosine (Flucytosine) is an organofluorine compound and antifungal agent, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida, neoplasm infection, as well as anticaner acitvities. |
| PC-21771 |
TH7528
SAMHD1 inhibitor
|
TH7528 (TH-7528) is a specific small-molecule inhibitor against the dNTP triphosphohydrolase (dNTPase) SAMHD1, inhibits the enzymatic activities of SAMHD1 against dGTP, Cl-F-ara-ATP, and ara-CTP with IC50 of 4.5, 2.8 and 2.6 uM, respectively. |
| PC-72483 |
MRT00252040
PAICS inhibitor
|
MRT00252040 (PAICSi) is a small molecule inhibitor PAICS, which catalyzes two steps in the de novo purine synthesis pathway. |
