| Cat. No. |
Product Name |
Information |
| PC-26912 |
Leucovorin
Antifolate
|
Leucovorin (folinic acid, calcium folinate) is a prescription form of reduced folic acid that does not require enzymatic activation by dihydrofolate reductase (DHFR), prevents side effects from certain medications, such as methotrexate. |
| PC-26703 |
PSB-24379
CD39 inhibitor
|
PSB-24379 is a potent, selective inhibitor of ATP-hydrolyzing ectoenzyme nucleoside triphosphate diphosphohydrolase-1 (NTPDase1, CD39) with Ki of 77.4 nM, shows ancillary CD73 inhibition with Ki of 240 nM. |
| PC-26077 |
MSD-914
ACHY inhibitor
|
MSD-914 is a potent, selective S-adenosylhomocysteine hydrolase (AHCY) inhibitor with IC50 of 40 nM, shows broad-spectrum in vitro anti-filovirus activity against EBOV, Marburg virus, and Sudan ebolavirus. |
| PC-24830 |
N3PT
Transketolase inhibitor
|
N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor, N3PT is pyrophosphorylated and then binds to transketolase with Kd of 22 nM. |
| PC-24757 |
POM-1
CD39 inhibitor
|
POM-1 (Sodium metatungstate, Sodium polyoxotungstate) is an effective NTPDase inhibitor with Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1 (CD39), NTPDase 3 and NTPDase 2 respectively, inhibits ATP breakdown and shows anti-inflammatory and anti-cancer effect. |
| PC-22737 |
Azathioprine
Purine synthesis inhibitor
|
Azathioprine (BW 57-322) is a purine synthesis inhibitor and orally active immunosuppressive agent. |
| PC-22447 |
L-Isoleucine
Nucleoside analog
|
L-isoleucine is the L-enantiomer of isoleucine, has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. |
| PC-22379 |
5-Fluorocytosine
Nucleoside analog
|
5-Fluorocytosine (Flucytosine) is an organofluorine compound and antifungal agent, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida, neoplasm infection, as well as anticaner acitvities. |
| PC-21771 |
TH7528
SAMHD1 inhibitor
|
TH7528 (TH-7528) is a specific small-molecule inhibitor against the dNTP triphosphohydrolase (dNTPase) SAMHD1, inhibits the enzymatic activities of SAMHD1 against dGTP, Cl-F-ara-ATP, and ara-CTP with IC50 of 4.5, 2.8 and 2.6 uM, respectively. |
| PC-72483 |
MRT00252040
PAICS inhibitor
|
MRT00252040 (PAICSi) is a small molecule inhibitor PAICS, which catalyzes two steps in the de novo purine synthesis pathway. |
| PC-36085 |
Aspacytarabine
|
Aspacytarabine (Astarabine, BST236) is a cytarabine conjugate that shows anti-neoplastic agents for inhibiting cancer cell growth. . |
| PC-35560 |
Elacytarabine
|
Elacytarabine (CP-4055, CP4055, ELACYT) is a fatty acid derivative of cytarabine with potential antineoplastic activity. |
