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Cat. No. Product Name Information
PC-61684

6-Ethylthioinosine

6-Ethylthioinosine (6-ETI, NSC 39368, SRI 1215) is a nucleoside analog that effectively and selectively inhibits Primary effusion lymphoma (PEL) in vitro and in vivo, but not to other lymphoma cell lines.
PC-61365

Cedazuridine

Cedazuridine (E7727) is a novel cytidine deaminase inhibitor, and a componet of ASTX727 for treatment of hematologic malignancies..
PC-70217

NSAH

Ribonucleotide reductase inhibitor

Ribonucleotide reductase inhibitor NASH is a nonnucleoside, competitive, small-molecule inhibitor of human ribonucleotide reductase (hRR) that binds to the large subunit hRRM1 at the catalytic site (C-site) with Kd of 37.4 uM, IC50 of 32 uM.
PC-46012

5-Fluorouracil

An uridine analog that is a widely used chemotherapeutic agent.
PC-45149

Gemcitabine

Gemcitabine (NSC 613327, LY188011) is a synthetic pyrimidine nucleoside prodrug that works by ihibiting the enzyme ribonucleotide reductase (RNR) and blocking the creation of new DNA.
PC-42402

MT-DADMe-ImmA

A stable transition state analogue and inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP) with dissociation constant of 86 pM.
PC-45630

Didox

Ribonucleotide reductase inhibitor

Didox is a ribonucleotide reductase (RNR) inhibitor; overcomes Bcl-2 mediated radiation resistance in PC-3 cells, inhibits LPS-induced mRNA levels of iNOS, IL-6, IL-1, TNF-α, NF-κβ (p65), and p38-α.
PC-42711

Raltitrexed

A quinazoline antifolate thymidylate synthase (TS) inhibitor with Ki of 62 nM.
PC-42266

Triapine

Ribonucleotide reductase inhibitor

Triapine (3-AP, PAN-811, OCX191, NSC 663249) is a potent ribonucleotide reductase (RNR) inhibitor with broad spectrum antitumor activity.
PC-42285

Acelarin

Acelarin (NUC-1031, CPF-31) is a gemcitabine phosphoramidate prodrug that can overcome the key cancer resistance
PC-45223

Tegafur

A chemotherapeutic prodrug of 5-flourouracil (5-FU) used in the treatment of cancers.
PC-42672

5-Azacytidine

A chemical analog of Cytidine that inhibits DNA methyltransferase.

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