Cat. No. |
Product Name |
Information |
PC-49466 |
GSK-3923868
PI4KB inhibitor
|
GSK-3923868 (PI4KB inhibitor 30) is a potent, selective, slow-dissociating PI4KB (PI4kIII-beta) inhibitor with pKi of 9.8, >1000-fold selectivity over PI4KA, inhibits HRV viral replication in COPD BECs. |
PC-73080 |
AZ3
PI4KB inhibitor
|
AZ3 (PI4KB inhibitor 3) is a seletive PI4KB inhibitor with pIC50 of 7.8, shows good lipid kinase selectivity (pIC50 5.1, 4.7 and 4.0 for PI4Kα, PI3Kα and PIP5Kγ respectively). |
PC-73079 |
AZ7
PI4KA inhibitor
|
AZ7 (PI4KA inhibitor 7) is a potent, selective PI4KA inhibitor with pIC50 of 8.2, >100-fold selectivity over PI4Kβ, PI3Kα and PIP5Kγ. |
PC-73078 |
Pipinib
PI4KB inhibitor
|
Pipinib is a small molecule Hedgehog signaling inhibitior by selective inhibition of phosphatidylinositol 4-kinase IIIβ (PI4KB, IC50=2.2 uM), inhibits Purmorphamine-induced osteogenesis with IC50 of 0.6 uM. |
PC-35292 |
UCT943
PI4K inhibitor
|
UCT943 (UCT-943) is a potent, selective, next generation Plasmodium falciparum PI4K inhibitor with IC50 of 23 nM. |
PC-35278 |
UCB9608
PI4KIIIβ inhibitor
|
UCB9608 (UCB-9608) is a potent, selective, orally bioavailable PI4KIIIβ inhibitor with IC50 of 11 nM. |
PC-35202 |
GSK-A1
PI4KA inhibitor
|
PI4KA inhibitor A1 (GSK-A1) is a highly specific and potent inhibitor of Phosphatidylinositol 4-kinase IIIα (PI4KIIIα). |
PC-63343 |
T-00127-HEV1
PI4KB inhibitor
|
T-00127-HEV1 is a broad-spectrum antienterovirus compound that selectively inhibits PI4KB activity with IC50 of 60 nM, inhibits poliovirus pseudovirus and EV71 in RD cells with IC50 of 0.77 and 0.73 uM. |
PC-63342 |
AL-9
PI4KIIIα inhibitor
|
AL-9 is a small molecule HCV replication inhibitor with EC50 of 0.29 and 0.75 uM for genotype 1b and 2a, inhibits purified PI4KIIIα with IC50 of 0.57 uM. |
PC-63341 |
BF738735
PI4KB inhibitor
|
BF738735 is a novel, broad-spectrum inhibitor of enterovirus replication (EC50=4-71 nM) that specifically targets host cell factor PI4KIIIβ with IC50 of 5.7 nM, 300-fold less potent for PI4KIIIα (IC50=1.7 uM). |
PC-42861 |
PIK-93
PI4K inhibitor
|
PIK-93 is a potent, synthetic PI4K inhibitor with IC50 of 19 nM (PI4KIIIβ), also inhibits PI3Kγ and PI3Kα with IC50 of 16 nM and 39 nM, respectively. |
PC-61696 |
KDU691
PI4K inhibitor
|
KDU691 is a potent, selective, orally active parasite PI4K inhibitor with IC50 of 1.5 nM for P. vivax PI4K (PvPI4K). |