Cat. No. |
Product Name |
Information |
PC-49466 |
GSK-3923868
PI4KB inhibitor
|
GSK-3923868 (PI4KB inhibitor 30) is a potent, selective, slow-dissociating PI4KB (PI4kIII-beta) inhibitor with pKi of 9.8, >1000-fold selectivity over PI4KA, inhibits HRV viral replication in COPD BECs. |
PC-73080 |
AZ3
PI4KB inhibitor
|
AZ3 (PI4KB inhibitor 3) is a seletive PI4KB inhibitor with pIC50 of 7.8, shows good lipid kinase selectivity (pIC50 5.1, 4.7 and 4.0 for PI4Kα, PI3Kα and PIP5Kγ respectively). |
PC-73079 |
AZ7
PI4KA inhibitor
|
AZ7 (PI4KA inhibitor 7) is a potent, selective PI4KA inhibitor with pIC50 of 8.2, >100-fold selectivity over PI4Kβ, PI3Kα and PIP5Kγ. |
PC-73078 |
Pipinib
PI4KB inhibitor
|
Pipinib is a small molecule Hedgehog signaling inhibitior by selective inhibition of phosphatidylinositol 4-kinase IIIβ (PI4KB, IC50=2.2 uM), inhibits Purmorphamine-induced osteogenesis with IC50 of 0.6 uM. |
PC-35278 |
UCB9608
PI4KIIIβ inhibitor
|
UCB9608 (UCB-9608) is a potent, selective, orally bioavailable PI4KIIIβ inhibitor with IC50 of 11 nM. |
PC-35202 |
GSK-A1
PI4KA inhibitor
|
PI4KA inhibitor A1 (GSK-A1) is a highly specific and potent inhibitor of Phosphatidylinositol 4-kinase IIIα (PI4KIIIα). |
PC-42861 |
PIK-93
PI4K inhibitor
|
PIK-93 is a potent, synthetic PI4K inhibitor with IC50 of 19 nM (PI4KIIIβ), also inhibits PI3Kγ and PI3Kα with IC50 of 16 nM and 39 nM, respectively. |
PC-61696 |
KDU-691
|
KDU-691 is a potent, selective, orally active parasite PI4K inhibitor with IC50 of 1.5 nM for P. vivax PI4K (PvPI4K). |
PC-61695 |
BQR-695
|
BQR-695 (NVP-BQR695) is a highly potent, selective PI4KIIIβ inhibitor that has high potency against both the human (IC50 = 80 nM) and PvPI4K (IC50=3.5 nM) . |
PC-61691 |
MMV390048
|
MMV390048 is a novel potent Plasmodium PI4K inhibitor with IC50 of 28 nM against intraerythrocytic life cycle stages of P. falciparum (NF54 drug-sensitive strain). |
PC-61327 |
PI-273
|
PI-273 (PI273) is a potent, specific, substrate-competitive small molecule inhibitor of PI4KIIα with IC50 of 0.47 uM. |
PC-35292 |
UCT943
|
UCT943 (UCT-943) is a potent, selective, next generation Plasmodium falciparum PI4K inhibitor with IC50 of 23 nM. |