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Cat. No. Product Name Information
PC-24219

UNC3810A

TYRO3 inhibitor

UNC3810A (UNC3810) is a potent, selective Tyro3 kinase inhibitor of IC50 of 1.2 nM, >10-fold selectivity versus all other kinases beyond MerTK, the most closely related TAM member, and TRKA.
PC-24218

UNC9426

TYRO3 inhibitor

UNC9426 is a potent, specific TYRO3 inhibitor with IC50 of 2.1 nM, has 276- and 90-fold selectivity over MERTK and AXL respectively.
PC-23043

UNC2541

Mer inhibitor

UNC2541 is a potent, specific Mer tyrosine kinase (MerTK) inhibitor with IC50 of 4.4 nM, >25-fold selective over Tyro3, Axl, and FLT3, shows EC50 of 550 nM in pMerTK ELISA assays.
PC-23042

UNC8969

Mer/Axl inhibitor

UNC8969 is a potent, selective, macrocyclic dual MerTK/Axl inhibitor with IC50 of 1.1/5.3 nM respectively, >12-fold selectivity over TYRO3 and FLT3.
PC-23041

A-910

Mer/Axl inhibitor

A-910 is a highly potent and selective, orally active dual MerTK/Axl inhibitor with IC50 of 0.2/0.9 nM respectively, >200-fold selective over Tyro3.
PC-50012

S49076 hydrochloride

S49076 hydrochloride is a potent, ATP-competitive tyrosine kinase inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 of <20 nM, also potently inhibits the kinase activity of mutated isoforms of MET (D1246N, Y1248D, Y1248H) and FGFR1/2.

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