| Cat. No. |
Product Name |
Information |
| PC-63226 |
UNC569
Mer inhibitor
|
UNC569 is a potent, small-molecule Mer kinase inhibitor with IC50 of 2.9 nM, 37 nM and 48 nM for Mer, Axl and Tyro3, respectively. |
| PC-63225 |
UNC1666
Mer/FLT3 inhibitor
|
UNC1666 is a potent, specific dual Mer and Flt3 tyrosine kinase inhibitor with IC50 of 0.55 and 0.69 nM. |
| PC-43061 |
LDC1267
TAM receptor inhibitor
|
LDC1267 is a potent, highly selective TAM receptor (Tyro3, Axl and Mer) kinase inhibitor with IC50 of <5 nM/8 nM/29 nM for Tyro3, Axl and Mer, respectively. |
| PC-42993 |
UNC2025
Mer/FLT3 inhibitor
|
UNC2025 is a potent, orally bioavailable Mer/FLT3 dual inhibitor with IC50 of 0.74/0.8 nM, 700-fold less active against Met compared to Mer. |
| PC-62809 |
Axl-IN-21
|
Axl-IN-21 is a selective and potent inhibitor of wild-type Axl with IC50 of 2.2 nM. |
| PC-61679 |
UNC-1062
Mer inhibitor
|
UNC-1062 is a potent and selective Mer kinase inhibitor with IC50 of 1.1 nM, Ki of 0.33 nM. |
| PC-60247 |
RU-302
TAM receptor inhibitor
|
RU-302 is a small molecule pan-TAM inhibitor that targets the TAM Ig1-Gas6 interface, blocks Gas6-dependent TAM activation. |
| PC-60246 |
RU-301
TAM receptor inhibitor
|
RU-301 (RU301) is a small molecule pan-TAM inhibitor that targets the TAM Ig1-Gas6 interface, blocks Gas6-dependent TAM activation. |
| PC-42292 |
CEP-40783
AXL/c-Met inhibitor
|
CEP-40783 (CEP40783, RXDX-106) is a potent and selective AXL/c-Met inhibitor with IC50 of 7 nM/12 nM. |
| PC-20336 |
R428
Axl inhibitor
|
R428 (Bemcentinib, BGB324) is potent, selective and orally bioavailable inhibitor of Axl kinase with IC50 of 14 nM. |
| PC-20335 |
UNC2881
Mer inhibitor
|
UNC2881 (UNC-2881) is a potent selective Mer kinase inhibitor with IC50 of 4.3 nM, 84-fold selectivity over Axl and 58-fold over Tyro3. |
| PC-20334 |
NPS-1034
MET-AXL inhibitor
|
NPS-1034 (NPS1034) is a potent, dual MET and AXL inhibitor with IC50 of 48 and 10.3 nM, respectively. |
