| Cat. No. |
Product Name |
Information |
| PC-38468 |
NMS-873
p97/VCP inhibitor
|
NMS-873 (NMS873) is a potent, specific, cell-permeable, non-ATP competitive, allosteric inhibitor of VCP/p97 ATPase with IC50 of 30 nM. |
| PC-72870 |
FL-18
p97 inhibitor
|
FL-18 (p97 inhibitor FL-18) is is the first small-molecule covalent inhibitor of VCP/p97 AAA ATPase with IC50 of 59.3 nM, capable of covalent engagement of p97 with proteome-wide selectivity. |
| PC-72409 |
CB-5339
VCP/p97 inhibitor
|
CB-5339 (CB5339) is a second-generation, potent, selective, ATP-competitive, and oral inhibitor of valosin-containing protein (VCP/p97) with IC50 of 9 nM. |
| PC-36136 |
LC-1028
p97/VCP inhibitor
|
LC-1028 (LC1028) is a novel potent selective, covalent and irreversible inhibitor of p97 (valosin-containing protein, VCP), remains essentially irreversible aciivity against p97 mutant C522A. |
| PC-35960 |
NPD8733
p97 inhibitor
|
NPD8733 (NPD-8733) is a small-molecule ligand of valosin-containing protein (VCP)/p97, binds to the D1 domain of VCP/p97. |
| PC-63243 |
UPCDC-30245
p97/VCP inhibitor
|
UPCDC-30245 is a potent, cell penetrant allosteric p97/VCP inhibitor with IC50 of 300 nM (WT p97), also potently inhibits CB-5083 resistant p97 D649A/T688A mutant. |
| PC-43263 |
CB-5083
p97 inhibitor
|
CB-5083 is a potent, selective, orally bioavailable inhibitor of p97/VCP AAA ATPase with IC50 of 11 nM, specifically targets D2 ATPase site of p97, shows 9.6, 128 and 158-fold less affinity for DNA-PK, mTOR and PIK3C3. |
| PC-62542 |
MSC1094308
p97/VPS4B inhibitor
|
MSC1094308 (MSC 1094308) is a reversible, allosteric inhibitor of the type II AAA ATPase human ubiquitin-directed unfoldase (VCP)/p97 and the type I AAA ATPase VPS4B with IC50 of 7.2 and 0.71 uM, respectively. |
| PC-45718 |
ML-241
p97 inhibitor
|
ML241 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM). |
| PC-45719 |
ML-241 hydrochloride
p97 inhibitor
|
ML241 hydrochloride is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM). |
| PC-45717 |
ML240
p97 inhibitor
|
ML240 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM). |
| PC-26297 |
p97 inhibitor PPA
VCP/p97 inhibitor
|
p97 inhibitor PPA (ACJI-99C) is a selective, covalent p97/VCP ATPase inhibitor with IC50 of 0.6 uM in in vitro ATPase activity assay, with no activity against yeast Cdc48, and N-ethylmaleimide sensitive factor (NSF). |
