| Cat. No. |
Product Name |
Information |
| PC-43263 |
CB-5083
p97 inhibitor
|
CB-5083 is a potent, selective, orally bioavailable inhibitor of p97/VCP AAA ATPase with IC50 of 11 nM, specifically targets D2 ATPase site of p97, shows 9.6, 128 and 158-fold less affinity for DNA-PK, mTOR and PIK3C3. |
| PC-62542 |
MSC 1094308
VCP/p97 inhibitor
|
MSC1094308 (MSC 1094308) is a reversible, allosteric inhibitor of the type II AAA ATPase human ubiquitin-directed unfoldase (VCP)/p97 and the type I AAA ATPase VPS4B with IC50 of 7.2 and 0.71 uM, respectively. |
| PC-45718 |
ML-241
p97 inhibitor
|
ML241 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM). |
| PC-45719 |
ML-241 hydrochloride
p97 inhibitor
|
ML241 hydrochloride is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM). |
| PC-45717 |
ML-240
p97 inhibitor
|
ML240 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM). |
| PC-24319 |
DBeQ
p97/VCP inhibitor, VPS4 inhibitor
|
DBeQ is a selective, potent, reversible, and ATP-competitive AAA ATPase p97/VCP inhibitor with IC50 of 1.5 μM and 1.6 μM for p97(wt) and p97(C522A) respectively, also inhibits VPS4 with IC50 of 11.5 uM. |
| PC-22873 |
Thonzonium bromide
p97-Npl4 inhibitor
|
Thonzonium bromide is an antibacterial agent, inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo, also is a ATPase p97-Npl4 interaction, boosts antitumor immunity without affecting peripheral Treg cell homeostasis. |
| PC-20932 |
UPCDC-30766
p97/VCP inhibitor
|
UPCDC-30766 (UPCDC 30766) is a potent, allosteric inhibitor of AAA+ ATPase p97 (valosin-containing protein, VCP) with biochemical IC50 of 12 nM, EC50 of 226 nM in cellular UbG76V-GFP accumulation assays. |
