| Cat. No. |
Product Name |
Information |
| PC-61416 |
LY2780301
p70S6K/Akt inhibitor
|
LY2780301 is a potent, highly selective, ATP-competitive dual inhibitor of p70S6K and Akt under development for the treatment of solid tumours and non-Hodgkin's lymphoma. |
| PC-70086 |
BI-69A11
Akt inhibitor
|
BI-69A11 is a potent, selective, ATP competitive AKT inhibitor with IC50 of 2.3 uM for Akt1. |
| PC-45738 |
SC-66
Akt inhibitor
|
SC66 is an allosteric Akt inhibitor, exhibits a dual inhibitory activity that directly interferes with the PH domain binding to PIP3 and facilitates Akt ubiquitination. |
| PC-42485 |
TCMDC-136364
Akt inhibitor
|
TCMDC-136364 (AKT Kinase Inhibitor) is an Akt kinase inhibitor, selectively inhibits Akt in proliferating cells expressing Trop-2, also potently inhibits P. falciparum multidrug resistant strain Dd2. |
| PC-45548 |
Akt activator SC79
Akt activator
|
SC-79 is a unique specific Akt activator, binds to the PH domain of Akt and inhibits Akt membrane translocation, but paradoxically activates Akt in the cytosol. |
| PC-42550 |
AKT inhibitor VIII
Akt inhibitor
|
AKT inhibitor VIII is a selective, allosteric Akt inhibitor with IC50 of 58/210 for Akt1/2 respectively. |
| PC-44665 |
Afuresertib hydrochloride
Akt inhibitor
|
Afuresertib (GSK2110183) hydrochloride potent, selective, ATP-competitive pan-AKT inhibitor with biochemical IC50 of 0.08/2/2.6 nM for AKT1/2/3. |
| PC-44664 |
Afuresertib
Akt inhibitor
|
Afuresertib (GSK2110183) is a potent, selective, ATP-competitive pan-AKT inhibitor with biochemical IC50 of 0.08/2/2.6 nM for AKT1/2/3. |
| PC-45876 |
Akt1/2-IN-17
Akt1/2 inhibitor
|
Akt1/2-IN-17 is a potent, selective dual Akt1 and Akt2 inhibitor with IC50 of 3.5 nM and 42 nM, respectively. |
| PC-42551 |
MK 2206 dihydrochloride
Akt inhibitor
|
MK 2206 dihydrochloride is a potent, orally active allosteric Akt inhibitor with IC50 of 5/12 nM for Akt1/Akt2 respectively. |
| PC-42484 |
GSK-690693
Akt inhibitor
|
GSK-690693 (GSK690693) is a potent, ATP competitive, pan-AKT inhibitor with IC50 of 2, 13, and 9 nM against AKT1, 2, and 3, respectively. |
| PC-42579 |
A-443654
Akt inhibitor
|
Rizavasertib (A-443654) is a potent and selective Akt inhibitor with Ki of 0.16 nM for Akt1/2/3. |
