| Cat. No. |
Product Name |
Information |
| PC-42485 |
TCMDC-136364
Akt inhibitor
|
TCMDC-136364 (AKT Kinase Inhibitor) is an Akt kinase inhibitor, selectively inhibits Akt in proliferating cells expressing Trop-2, also potently inhibits P. falciparum multidrug resistant strain Dd2. |
| PC-45548 |
Akt activator SC79
Akt activator
|
SC-79 is a unique specific Akt activator, binds to the PH domain of Akt and inhibits Akt membrane translocation, but paradoxically activates Akt in the cytosol. |
| PC-42550 |
AKT inhibitor VIII
Akt inhibitor
|
AKT inhibitor VIII is a selective, allosteric Akt inhibitor with IC50 of 58/210 for Akt1/2 respectively. |
| PC-44665 |
Afuresertib hydrochloride
Akt inhibitor
|
Afuresertib (GSK2110183) hydrochloride potent, selective, ATP-competitive pan-AKT inhibitor with biochemical IC50 of 0.08/2/2.6 nM for AKT1/2/3. |
| PC-44664 |
Afuresertib
Akt inhibitor
|
Afuresertib (GSK2110183) is a potent, selective, ATP-competitive pan-AKT inhibitor with biochemical IC50 of 0.08/2/2.6 nM for AKT1/2/3. |
| PC-45876 |
Akt1/2-IN-17
Akt1/2 inhibitor
|
Akt1/2-IN-17 is a potent, selective dual Akt1 and Akt2 inhibitor with IC50 of 3.5 nM and 42 nM, respectively. |
| PC-42551 |
MK 2206 dihydrochloride
Akt inhibitor
|
MK 2206 dihydrochloride is a potent, orally active allosteric Akt inhibitor with IC50 of 5/12 nM for Akt1/Akt2 respectively. |
| PC-42484 |
GSK-690693
Akt inhibitor
|
GSK-690693 (GSK690693) is a potent, ATP competitive, pan-AKT inhibitor with IC50 of 2, 13, and 9 nM against AKT1, 2, and 3, respectively. |
| PC-42579 |
A-443654
Akt inhibitor
|
A-443654 is a potent and selective Akt inhibitor with Ki of 0.16 nM for Akt1. |
| PC-42032 |
BAY-1125976
Akt inhibitor
|
BAY-1125976 is a potent and highly selective, allosteric AKT1/2 inhibitor with IC50 of 5.2/18 nM at 10 uM ATP. |
| PC-45903 |
Perifosine
Akt inhibitor
|
Perifosine (KRX-0401, D21266) is an oral bioavailable alkylphospholipid, acts as an Akt inhibitor and a PI3K inhibitor, induces p21(WAF1) expression in squamous carcinoma cells through a p53-independent pathway. |
| PC-42697 |
PF-AKT400
Akt inhibitor
|
PF-AKT400 is a broadly selective, potent, ATP-competitive Akt kinase inhibitor with IC50 of 0.5 nM (biochemical assay), and 0.31 nM (cell function assay). |
