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Cat. No. Product Name Information
PC-42244

S63845

Mcl-1 inhibitor

S63845 is a highly potent, selective Mcl-1 inhibitor with Kd of 0.19 nM, with no appreciable binding affinity to BCL-2 or BCL-XL (Ki>10 uM).
PC-47486

Bax inhibitor peptide V5

Bax inhibitor

Bax inhibitor peptide V5 (Val-Pro-Met-Leu-Lys, BIP-V5) is cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation.
PC-45901

ABT-737

BCL-2 inhibitor

ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively.
PC-28265

BFL-1 inhibitor 20

Bfl-1 inhibitor

BFL-1 inhibitor 20 (Bfl-1-IN-6) is a potent, selective, covalent and orally bioavailable BFL-1 inhibitor with IC50 of 19 nM in TR-FRET assays, binds to Cys55 of BFL1.

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