| Cat. No. |
Product Name |
Information |
| PC-42244 |
S63845
Mcl-1 inhibitor
|
S63845 is a highly potent, selective Mcl-1 inhibitor with Kd of 0.19 nM, with no appreciable binding affinity to BCL-2 or BCL-XL (Ki>10 uM). |
| PC-47486 |
Bax inhibitor peptide V5
Bax inhibitor
|
Bax inhibitor peptide V5 (Val-Pro-Met-Leu-Lys, BIP-V5) is cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. |
| PC-45901 |
ABT-737
BCL-2 inhibitor
|
ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively. |
| PC-28265 |
BFL-1 inhibitor 20
Bfl-1 inhibitor
|
BFL-1 inhibitor 20 (Bfl-1-IN-6) is a potent, selective, covalent and orally bioavailable BFL-1 inhibitor with IC50 of 19 nM in TR-FRET assays, binds to Cys55 of BFL1. |