| Cat. No. |
Product Name |
Information |
| PC-38690 |
Zavegepant
CGRP antagonist
|
Zavegepant (Vazegepant, BHV-3500, BMS-742413) is a high affinity, selective antagonist of calcitonin gene-related peptide (CGRP) receptor (hCGRP, Ki=0.023 nM), has demonstrated efficacy in the acute treatment of migraine. |
| PC-72952 |
BMS-846372
CGRP antagonist
|
BMS-846372 (BMS846372) is a potent, selective, orally active CGRP receptor antagonist with Ki of 0.07 nM (hCGRP). |
| PC-72787 |
FE 205030
CGRP antagonist
|
FE 205030 (FE205030) is a potent, selective peptidic CGRP antagonist with IC50 of 0.2 nM. |
| PC-35253 |
Ubrogepant
CGRP inhibitor
|
Ubrogepant (MK-1602) is a novel potent, selective, oral calcitonin gene-related peptide receptor (CGRP) antagonist for acute treatment of migraine.. |
| PC-62994 |
MK-8825
CGRP inhibitor
|
MK-8825 is a highly potent, selective, orally bioavailable CGRP receptor antagonist with Ki of 17 nM for rat CGRP. |
| PC-60031 |
Atogepant
CGRP inhibitor
|
Atogepant (MK-8031) is a potent and selective calcitonin gene-related peptide (CGRP) receptor antagonist with Ki of 2 pM (hCGRP). |
| PC-42296 |
Olcegepant hydrochloride
CGRP inhibitor
|
Olcegepant hydrochloride (BIBN4096BS) is the first small molecule selective calcitonin gene-related peptide (CGRP) receptor antagonist with Ki of 14.4 nM for hCGRP. |
| PC-42294 |
Olcegepant
CGRP antagonist
|
Olcegepant (BIBN-4096, BIBN4096BS) is the first small molecule selective calcitonin gene-related peptide (CGRP) receptor antagonist with Ki of 14.4 nM for hCGRP. |
| PC-45811 |
MK-0974
CGRP inhibitor
|
Telcagepant (MK-0974) is a potent, selective, orally bioavailable CGRP receptor antagonist with Ki of 0.77 nM. |
| PC-42516 |
MK-3207
CGRP inhibitor
|
MK-3207 is a highly potent, selective CGRP receptor antagonist with Ki of 21 pM in in vitro binding assay and IC50 of 0.12 nM in cell-based functional assay. |
| PC-21792 |
Rimegepant
CGRP inhibitor
|
Rimegepant (BMS-927711) is a potent, selective and orally active calcitonin gene-related peptide (CGRP) antagonist with Ki of 0.027 nM, inhibits CGRP-stimulated cAMP production in SK-N-MC cells with EC50 of 0.14 nM. |
| PC-21156 |
BMS-694153
CGRP antagonist
|
BMS-694153 is a potent, selective calcitonin gene-related peptide (CGRP) receptor antagonist with Ki of 0.013 nM for hCGRP (inhibition of 125I-CGRP binding in SK-N-MC cell membranes). |
