| Cat. No. |
Product Name |
Information |
| PC-25294 |
CYP1A1 inhibitor 47
CYP1A1 inhibitor
|
CYP1A1 inhibitor 47 is a small molecule cytochrome P4501A1 (CYP1A1) inhibitor with IC50 of 0.2 uM and 0.01 uM in Caco-2 and CYhiRAW cells respectively, promotes macrophage phagocytosis, enhances macrophage-mediated bacterial clearance in vivo by inhibiting CYP1A1. |
| PC-25060 |
Seviteronel
CYP17A1 lyase inhibitor
|
Seviteronel (VT-464) is a potent, selective and oral inhibitor of CYP17A1 inhibitor with 17,20-lyase IC50 of 69 nM, 10-fold selective over 17α-hydroxylase. |
| PC-25058 |
CFG920
CYP17A1 inhibitor
|
CFG920 (Lapiteronel) is a potent, selective cytochrome P450c17 (CYP17A1) inhibitor. |
| PC-24523 |
17-ODYA
CYP450 inhibitor
|
17-ODYA (17-octadecynoic acid) is a CYP450 omega-hydroxylase ( CYP450 ω) inhibitor CYP450 ω-hydroxylase inhibitor, also inhibits the formation of 20-hydroxyeicosatetraenoic acid (20-HETE), epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids by rat renal cortical microsomes incubated with arachidonic acid. |
| PC-24397 |
SCM-08
CYP3A4 inhibitor
|
SCM-08 is a potent, selective, non-suicide CYP3A4 inhibitor with IC50 of 0.43 uM in P450-Glo inhibition assays, 47-fold selecitve over CYP3A5. |
| PC-24396 |
SCM-18
CYP3A4 inhibitor
|
SCM-18 is a potent, highly selective, non-suicide CYP3A4 inhibitor with IC50 of 0.36 uM, has >170 fold selectivity over CYP3A5 (IC50>60 uM). |
| PC-24395 |
SCM-01
CYP3A4 inhibitor
|
SCM-01 is a potent, selective, non-suicide CYP3A4 inhibitor with IC50 of 0.32 uM in P450-Glo inhibition assays, 14-fold selecitve over CYP3A5. |
| PC-23938 |
Ketoconazole
CYP3A4 inhibitor
|
Ketoconazole (R 41400) is an imidazole anti-fungal agent and CYP3A4 and CYP24A1 inhibitor. |
| PC-23802 |
CYP3cide
CYP3A4 inhibitor
|
CYP3cide (PF-04981517) is a potent, efficient, and specific time-dependent inhibitor of cytochrome P4503A4 (CYP3A4) with IC50 of 0.03 uM, >500-fold selective over CYP3A5 and CYP3A7. |
| PC-23328 |
CYP4A11 and CYP4F2 inhibitor 15
CYP4A11/4F2 inhibitor
|
CYP4A11 and CYP4F2 inhibitor 15 is a potent, dual inhibitor of cytochrome P450 (CYP) 4F2 and CYP4A11 (CYP4A11/4F2) with IC50 of 120/220 nM respectively, exhibits potent suppression of 20-HETE production in both human and rat renal microsomes with IC50 of 18 nM and 37 nM. |
| PC-23290 |
CYP2E1 inhibitor Q11
CYP2E1 inhibitor
|
CYP2E1 inhibitor Q11 is a specific Cytochrome P450 2E1 (CYP2E1) inhibitor with Ki of 897 nM. |
| PC-21449 |
Dual CYP19A1/CYP11B2 inhibitor X21
CYP19A1/CYP11B2 inhibitor
|
Dual CYP19A1/CYP11B2 inhibitor X21 is a potent and selective dual inhibitor of aromatase (CYP19A1) and aldosterone synthase (CYP11B2) with IC50 of 2.3 nM and 29 nM, respectively. |
