| Cat. No. |
Product Name |
Information |
| PC-45937 |
Abiraterone
CYP17A1 inhibitor
|
Abiraterone (CB-7598) is a potent and irreversible CYP17A1 inhibitor with IC50 of 4 nM for 17α-hydroxylase. |
| PC-45958 |
Abiraterone acetate
CYP17A1 inhibitor
|
Abiraterone acetate (CB-7598) is a potent and irreversible CYP17A1 inhibitor with IC50 of 4 nM for 17α-hydroxylase. |
| PC-45936 |
TOK-001
CYP17 inhibitor
|
TOK-001 (Galeterone) is a potent 17α-hydroxylase/17,20-lyase (CYP17) inhibitor with IC50 of 300 nM. |
| PC-42617 |
Cobicistat
CYP3A inhibitor
|
Cobicistat (GS-9350) is a pharmacoenhancer that acts as potent and selective inhibitor of human CYP3A with IC50 of 30-285 nM. |
| PC-45969 |
Bergaptol
CYP3A4 inhibitor
|
Bergaptol is a natural furanocoumarin that is found to be a potent inhibitor of debenzylation activity of CYP3A4 enzyme with IC50 of 24.92 uM. |
| PC-42626 |
Orteronel
CYP17A1 inhibitor
|
Orteronel (TAK-700) is a highly selective CYP17A1 (17,20-lyase) inhibitor with IC50 of 17 nM for human 17,20-lyase. |
| PC-23328 |
CYP4A11 and CYP4F2 inhibitor 15
CYP4A11/4F2 inhibitor
|
CYP4A11 and CYP4F2 inhibitor 15 is a potent, dual inhibitor of cytochrome P450 (CYP) 4F2 and CYP4A11 (CYP4A11/4F2) with IC50 of 120/220 nM respectively, exhibits potent suppression of 20-HETE production in both human and rat renal microsomes with IC50 of 18 nM and 37 nM. |
| PC-23290 |
CYP2E1 inhibitor Q11
CYP2E1 inhibitor
|
CYP2E1 inhibitor Q11 is a specific Cytochrome P450 2E1 (CYP2E1) inhibitor with Ki of 897 nM. |
| PC-21449 |
Dual CYP19A1/CYP11B2 inhibitor X21
CYP19A1/CYP11B2 inhibitor
|
Dual CYP19A1/CYP11B2 inhibitor X21 is a potent and selective dual inhibitor of aromatase (CYP19A1) and aldosterone synthase (CYP11B2) with IC50 of 2.3 nM and 29 nM, respectively. |
| PC-21418 |
TPP-IOA
Cyt c peroxidase inhibitor
|
TPP-IOA is a specific inhibitor of cytochrome c (cyt c) peroxidase activity, inhibits peroxidase activity of cardiolipin-induced cytochrome c peroxidase activity with IC50 of 5 uM. |
| PC-20707 |
TP0472993
20-HETE synthesis inhibitor
|
TP0472993 is a potent, selective 20-Hydroxyeicosatetraenoic acid (20-HETE) synthesis inhibitor, inhibits 20-HETE formation in human and rat renal microsomes with IC50 of 29 and 347 nM, respectively. |
| PC-49301 |
BMS-737
CYP17 lyase inhibitor
|
BMS-737 (BMS737) is a potent, , selective, non-steroidal, reversible inhibitor of CYP17 lyase, 11-fold selectivity for CYP17 lyase over CYP17 hydroxylase. |
