| Cat. No. |
Product Name |
Information |
| PC-72679 |
8-BOA
CYP4Z1 inhibitor
|
8-BOA is a selective and potent mechanism-based inactivator of breast cancer-associated CYP4Z1. |
| PC-35319 |
HET0016
CYP4A inhibitor
|
HET0016 (HET-0016) is a potent, selective inhibitor of CYP4A, potently inhibits the formation of 20-HETE with IC50 of 8.9 nM in human renal microsomes. |
| PC-63002 |
YM116
CYP17A1 inhibitor
|
YM116 is a potent CYP17A1 (17,20-lyase) inhibitor with IC50 with Ki of 0.38 nM, inhibits C17-20 lyase activity in human testicular microsomes with IC50 of 4.2 nM. |
| PC-62112 |
ML368
CYP3A4 inhibitor
|
ML368 (SR9186) is a potent, selective cytochrome P450 enzyme CYP3A4 inhibitor with IC50 of 4 nM (convert testosterone to hydroxytestosterone), displays >2,000-fold selectivity over CYP3A5. |
| PC-61908 |
N1-hexyl-N5-benzyl-biguanide mesylate
CYP3A4 inhibitor
|
N1-hexyl-N5-benzyl-biguanide mesylate (HBB) is a potent and specific inhibitor of CYP3A4 AA epoxygenase activity with IC50 of 9.5 uM for inhibition of CYP3A4-mediated (±)-14,15-EET synthesis. |
| PC-61692 |
CYP11B1-IN-25
CYP11B1 inhibitor
|
CYP11B1-IN-25 is a selective, potent 11β-hydroxylase (CYP11B1) inhibitor with IC50 of 2 nM, displays 14-fold selectivity over CYP11B2. |
| PC-70290 |
R-116010
CYP26A1 inhibitor
|
R-116010 is a potent CYP26A1 inhibitor with IC50 of 10 nM, potently inhibits all-trans-retinoic acid metabolism in intact T47D cells with IC50 of 8.7 nM. |
| PC-60700 |
BI 689648
CYP11B2 inhibitor
|
BI 689648 is a potent, selective, orally active aldosterone synthase (CYP11B2) inhibitor with IC50 of 2 nM, displays 150-fold selectivity over related cortisol synthase ((CYP11B1). |
| PC-42290 |
CDD3506
CYP3A inducer
|
A small molecule inducer of hepatic cytochrome P450IIIA (CYP3A), produces significant increases in HDL cholesterol.. |
| PC-42289 |
CDD3505
CYP3A inducer
|
CDD3505 is a small molecule inducer of hepatic cytochrome P450IIIA (CYP3A), produces significant increases in HDL cholesterol. |
| PC-45788 |
Methoxsalen
CYP2A5/CYP2A6 inhibitor
|
Methoxsalen (8-Methoxypsoralen, Xanthotoxin, 8-MOP) is a potent tricyclic furocoumarin suicide that used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to sunlight. |
| PC-45614 |
CYP1B1 inhibitor TMS
CYP1B1 inhibitor
|
TMS is a potent and selective inhibitor of the EROD activity of P450 1B1 (CYP1B1) with IC50 of 6 nM |
