Diacylglycerol Lipase (DAGL) (inhibitors, antagonists, agonists)-ProbeChem.com

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Cat. No.	Product Name	Information
PC-20127	LEI-106 DAGL-α/ABHD6 inhibitor	LEI-106 (LEI 106) is a potent, dual DAGL-α/ABHD6 inhibitor with Ki values of 0.7/0.8 uM, respectively.
PC-20126	RHC-80267 DAGL inhibitor	RHC-80267 (U 57908) is a small molecule inhibitor of diacylglycerol lipase (DAGL) with IC50 values of 1.1 and 4 μM in rat cardiac myocytes and canine platelets respectively.
PC-20125	Orlistat Lipase inhibitor	Orlistat ((–)-Tetrahydrolipstatin, Ro-18-0647) is a small molecule inhibitor of pancreatic and gastric lipase, inhibits DAGLα, DAGLβ, ABHD12, ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH) with IC50 of 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively.
PC-62857	LEI-105 DAGL inhibitor	LEI-105 (LEI 105) is a potent, highly selective, and reversible dual DAGL-α/DAGL-β inhibitor with pIC50 of 7.5/7.4 respectively.
PC-61839	KT-172 DAGLβ inhibitor	KT-172 is a potent, selective inhibitor of DAGLβ with IC50 of 60 nM.
PC-61838	KT-109 DAGLβ inhibitor	KT-109 (KT109) is a potent, selective inhibitor of DAGLβ with IC50 of 42 nM, displays about 60-fold selectivity over DAGLα.
PC-61837	DAGL inhibitor DO34 DAGLα/β inhibitor	DAGL inhibitor DO34 is a highly potent dual DAGLα/β inhibitor with IC50 of 6 nM 3-8 nM, respectively.
PC-61836	DH-376 DAGLα/β inhibitor	DH-376 is a highly potent dual DAGLα/β inhibitor with IC50 of 6 nM and 3-8 nM, respectively.

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