Cat. No. |
Product Name |
Information |
PC-38389 |
Eragidomide
CRBN E3 ligase modulator
|
Eragidomide (CC-90009) is a first-in-class, GSPT1-selective cereblon E3 ligase modulator, selectively degrades GSPT1 (EC50=9 nM) resulting in acute AML apoptosis and elimination of disease-driving leukemia stem cells (LSCs). |
PC-73170 |
Lenalidomide-Br
E3 Ligase Ligand
|
Lenalidomide-Br is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase and recruitment of CRBN protein, can be used for PROTACs design. |
PC-73169 |
SY2-062
E3 Ligase Ligand
|
SY2-062 is a thalidomide derivative and useful precursor for synthesis of thalidomide-based PROTAC degrader. |