E3 Ubiquitin Ligase (inhibitors, antagonists, agonists)-ProbeChem.com

Request The Product List ofE3 Ubiquitin Ligase E3 Ubiquitin Ligase

Cat. No.	Product Name	Information
PC-24706	ZK-14i Skp2 inhibitor	ZK-14i (Skp2 inhibitor 14i) is a potent inhibitor of S-phase kinase-associated protein 2 (Skp2) with IC50 of 2.8 uM against the Skp2-Cks1 interaction.
PC-24524	GS143 E3 ligase β-TrCP inhibitor	GS143 is a specific small molecule inhibitor of E3 ligase β-TrCP, exhibits potent latency reversing agent (LRA) activity, also is a NF-kappaB signaling inhibitor, inhibits IκBα ubiquitylation (IC50=5.2 uM).
PC-23887	Hakin-1 Hakai inhibitor	Hakin-1 (Hakai inhibitor-1) is a specific small molecule inhibitor of the E3 ubiquitin-ligase Hakai, reduces Hakai-mediated total ubiquitination and Hakai-mediated ubiquitination of E-cadherin.
PC-22789	BC-1293 FBXO24 inhibitor	BC-1293 is a specific small molecule inhibitor of bacterial-induced ubiquitin E3 ligase subunit FBXO24, abrogates FBXO24-DARS2 binding, exhibits immunostimulatory properties.
PC-22418	PFI-E3H1 GID4 inhibitor	PFI-E3H1 is a potent, selective chemical handle of Gid4 subunit of the human E3 ligase CTLH degradation complex with IC50 of 2.5 uM in NanoBRET assay measuring the Gid4/MPGLWKS interaction.
PC-22417	PFI-7 GID4 inhibitor	PFI-7 is a potent, selective and cell-active chemical probe inhibitor for GID4, a substrate-binding receptor within the C-terminal to LisH (CTLH) E3 ligase complex.

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