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Cat. No. Product Name Information
PC-21555

C7683

Cbl-b inhibitor

C7683 is a small-molecule inhibitor of the RING-type E3 ubiquitin ligase Cbl-b with IC5 of <1 nM, an analogue of Nx-1607.
PC-21307

Smurf1 inhibitor 1

SMURF1 inhibitor

Smurf1 inhibitor 1 is a potent, selective Smurf1 E3 ligase inhibitor with IC50 of 230 nM in in UbFluor assays, inhibits the catalytic HECT domain of Smurf1.
PC-20919

SMURF1 inhibitor 29

SMURF1 inhibitor

SMURF1 inhibitor 29 is a potent, specific E3 ubiquitin protein ligase 1 (SMURF1) inhibitor with biochemical IC50 of 11 nM, displays no activity against SMURF2.
PC-20904

SMURF1 inhibitor 38

SMURF1 inhibitor

SMURF1 inhibitor 38 is a potent, specific E3 ubiquitin protein ligase 1 (SMURF1) inhibitor with biochemical IC50 of 92 nM, displays no activity against SMURF2.

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