Cat. No. |
Product Name |
Information |
PC-21555 |
C7683
Cbl-b inhibitor
|
C7683 is a small-molecule inhibitor of the RING-type E3 ubiquitin ligase Cbl-b with IC5 of <1 nM, an analogue of Nx-1607. |
PC-21307 |
Smurf1 inhibitor 1
SMURF1 inhibitor
|
Smurf1 inhibitor 1 is a potent, selective Smurf1 E3 ligase inhibitor with IC50 of 230 nM in in UbFluor assays, inhibits the catalytic HECT domain of Smurf1. |
PC-20919 |
SMURF1 inhibitor 29
SMURF1 inhibitor
|
SMURF1 inhibitor 29 is a potent, specific E3 ubiquitin protein ligase 1 (SMURF1) inhibitor with biochemical IC50 of 11 nM, displays no activity against SMURF2. |
PC-20904 |
SMURF1 inhibitor 38
SMURF1 inhibitor
|
SMURF1 inhibitor 38 is a potent, specific E3 ubiquitin protein ligase 1 (SMURF1) inhibitor with biochemical IC50 of 92 nM, displays no activity against SMURF2. |