| Cat. No. |
Product Name |
Information |
| PC-43264 |
GDC-0810
SERD
|
GDC-0810 (ARN-810, Brilanestrant) is a non-steroidal, orally bioavailable selective estrogen receptor degrader (SERD) with IC50 of 0.7 nM (ER-α degradation), binds to ERα and ERβ with with Ki of 3.8 and 3.7 nM, respectively. |
| PC-43234 |
BHPI
ERα inhibitor
|
BHPI is a potent, noncompetitive small molecule ERα inhibitor (biomodulator) that selectively blocks proliferation of drug-resistant ERα-positive breast and ovarian cancer cells. |
| PC-43041 |
Diarylpropionitrile
ERβ agonist
|
Diarylpropionitrile (DPN) is a non-steroidal estrogen receptor β(ERβ) selective ligand, demonstrates the neuroprotective effects against 10 0M Aβ1-42-induced oxidative stress and inflammation in primary rat cortical cell culture. |
| PC-42344 |
WAY-200070
ERβ agonist
|
WAY-200070 is a potent, highly selective ERβ agonist with IC50 of 3 nM, displays 68-fold selectivity over ERα (IC50=260 nM). |
| PC-70134 |
4-Hydroxytamoxifen
SERM
|
4-Hydroxytamoxifen (Afimoxifene) is a selective estrogen receptor modulator (SERM) and the major active metabolite of tamoxifen. |
| PC-70133 |
Droloxifene
SERM
|
Droloxifene (3-Hydroxytamoxifen; FK-435) is a nonsteroidal selective estrogen receptor modulator (SERM) that shows 10- to 60-fold increased affinity for the estrogen receptor compared with Tamoxifen. |
| PC-60267 |
PHTPP
ERβ inhibitor
|
PHTPP is a potent, selective antagonist of estrogen ERβ receptor, exhibits 36-fold selective for ERβ. |
| PC-60063 |
Enclomiphene citrate
|
Enclomiphene citrate((E)-Clomifene, cis-Clomifene, RMI-16289, ICI-46476) is a nonsteroidal selective estrogen receptor modulator (SERM) that is under development for the treatment of male hypogonadism. |
| PC-45734 |
Elacestrant dihydrochloride
|
Elacestrant (RAD-1901) is a novel, orally bioavailable small-molecule selective estrogen receptor degrader (SERD). |
| PC-45733 |
Elacestrant
SERD
|
Elacestrant (RAD-1901) is a novel, orally bioavailable small-molecule selective estrogen receptor degrader (SERD). |
| PC-43271 |
AZD9496 maleate
|
A potent, selective estrogen receptor downregulator (SERD) with ER downregulation pIC50 of 9.68. |
| PC-43270 |
AZD9496
Estrogen receptor inhibitor
|
AZD9496 is a potent, selective estrogen receptor downregulator (SERD) with ER downregulation pIC50 of 9.68. |
